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Anti-PIK3CD monoclonal antibody
Pre-made anti-PIK3CD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PIK3CD/PIK3CD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T67849-Ab-1/ GM-Tg-hg-T67849-Ab-2 | Anti-Human PIK3CD monoclonal antibody | Human |
| GM-Tg-rg-T67849-Ab-1/ GM-Tg-rg-T67849-Ab-2 | Anti-Rat PIK3CD monoclonal antibody | Rat |
| GM-Tg-mg-T67849-Ab-1/ GM-Tg-mg-T67849-Ab-2 | Anti-Mouse PIK3CD monoclonal antibody | Mouse |
| GM-Tg-cynog-T67849-Ab-1/ GM-Tg-cynog-T67849-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIK3CD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T67849-Ab-1/ GM-Tg-felg-T67849-Ab-2 | Anti-Feline PIK3CD monoclonal antibody | Feline |
| GM-Tg-cang-T67849-Ab-1/ GM-Tg-cang-T67849-Ab-2 | Anti-Canine PIK3CD monoclonal antibody | Canine |
| GM-Tg-bovg-T67849-Ab-1/ GM-Tg-bovg-T67849-Ab-2 | Anti-Bovine PIK3CD monoclonal antibody | Bovine |
| GM-Tg-equg-T67849-Ab-1/ GM-Tg-equg-T67849-Ab-2 | Anti-Equine PIK3CD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T67849-Ab-1/ GM-Tg-hg-T67849-Ab-2; GM-Tg-rg-T67849-Ab-1/ GM-Tg-rg-T67849-Ab-2; GM-Tg-mg-T67849-Ab-1/ GM-Tg-mg-T67849-Ab-2; GM-Tg-cynog-T67849-Ab-1/ GM-Tg-cynog-T67849-Ab-2; GM-Tg-felg-T67849-Ab-1/ GM-Tg-felg-T67849-Ab-2; GM-Tg-cang-T67849-Ab-1/ GM-Tg-cang-T67849-Ab-2; GM-Tg-bovg-T67849-Ab-1/ GM-Tg-bovg-T67849-Ab-2; GM-Tg-equg-T67849-Ab-1/ GM-Tg-equg-T67849-Ab-2 |
| Products Name | Anti-PIK3CD monoclonal antibody |
| Format | mab |
| Target Name | PIK3CD |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PIK3CD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T67849-Ag-1 | Recombinant multi-species PK3CD/ PIK3CD/ APDS protein |
Target information
| Target ID | GM-T67849 |
| Target Name | PIK3CD |
| Gene ID | 5293,18707,366508,710552,489644,101094274,504531,100051623 |
| Gene Symbol and Synonyms | 2410099E07Rik,2610208K16Rik,APDS,IMD14,IMD14A,IMD14B,p110D,P110DELTA,PI3K,PIK3CD,ROCHIS |
| Uniprot Accession | O00329 |
| Uniprot Entry Name | PK3CD_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000171608 |
| Target Classification | Kinase, Tumor-associated antigen (TAA) |
The target: PIK3CD, gene name: PIK3CD, also named as APDS, IMD14, P110DELTA, PI3K, p110D. Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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