Anti-GSK-3B monoclonal antibody

Pre-made anti-GSK-3B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GSK-3B/GSK3B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T70977-Ab-1/ GM-Tg-hg-T70977-Ab-2Anti-Human GSK-3B/GSK3B monoclonal antibodyHuman
GM-Tg-rg-T70977-Ab-1/ GM-Tg-rg-T70977-Ab-2Anti-Rat GSK-3B/GSK3B monoclonal antibodyRat
GM-Tg-mg-T70977-Ab-1/ GM-Tg-mg-T70977-Ab-2Anti-Mouse GSK-3B/GSK3B monoclonal antibodyMouse
GM-Tg-cynog-T70977-Ab-1/ GM-Tg-cynog-T70977-Ab-2Anti-Cynomolgus/ Rhesus macaque GSK-3B/GSK3B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T70977-Ab-1/ GM-Tg-felg-T70977-Ab-2Anti-Feline GSK-3B/GSK3B monoclonal antibodyFeline
GM-Tg-cang-T70977-Ab-1/ GM-Tg-cang-T70977-Ab-2Anti-Canine GSK-3B/GSK3B monoclonal antibodyCanine
GM-Tg-bovg-T70977-Ab-1/ GM-Tg-bovg-T70977-Ab-2Anti-Bovine GSK-3B/GSK3B monoclonal antibodyBovine
GM-Tg-equg-T70977-Ab-1/ GM-Tg-equg-T70977-Ab-2Anti-Equine GSK-3B/GSK3B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T70977-Ab-1/ GM-Tg-hg-T70977-Ab-2; GM-Tg-rg-T70977-Ab-1/ GM-Tg-rg-T70977-Ab-2;
GM-Tg-mg-T70977-Ab-1/ GM-Tg-mg-T70977-Ab-2; GM-Tg-cynog-T70977-Ab-1/ GM-Tg-cynog-T70977-Ab-2;
GM-Tg-felg-T70977-Ab-1/ GM-Tg-felg-T70977-Ab-2; GM-Tg-cang-T70977-Ab-1/ GM-Tg-cang-T70977-Ab-2;
GM-Tg-bovg-T70977-Ab-1/ GM-Tg-bovg-T70977-Ab-2; GM-Tg-equg-T70977-Ab-1/ GM-Tg-equg-T70977-Ab-2
Products NameAnti-GSK-3B/GSK3B monoclonal antibody
Target NameGSK-3B
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Products descriptionPre-made anti-GSK-3B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T70977-Ag-1Recombinant multi-species GSK3B/ GSK-3B protein
    ORF Viral VectorpGMAAV000150human GSK3B AAV plasmid
    ORF Viral VectorvGMAAV000150human GSK3B AAV particle

    Target information

    Target IDGM-T70977
    Target NameGSK-3B
    Gene ID2932,56637,84027,713114,478575,101081660,790875,100061033
    Gene Symbol and Synonyms7330414F15Rik,8430431H08Rik,GSK-3,GSK-3beta,GSK3,GSK3B,GSK3beta
    Uniprot AccessionP49841,P18266
    Uniprot Entry NameGSK3B_HUMAN,GSK3B_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000082701
    Target ClassificationKinase

    The target: GSK-3B, gene name: GSK3B, also named as . The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.