Anti-SNP25/ SNAP25/ CMS18 monoclonal antibody

Anti-SNP25/ SNAP25/ CMS18 antibody for FACS & in-vivo assay

Target products collectionGo to SNAP25/SNAP25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2Anti-Human SNAP25 monoclonal antibodyHuman
GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2Anti-Rat SNAP25 monoclonal antibodyRat
GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2Anti-Mouse SNAP25 monoclonal antibodyMouse
GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2Anti-Cynomolgus/ Rhesus macaque SNAP25 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2Anti-Feline SNAP25 monoclonal antibodyFeline
GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2Anti-Canine SNAP25 monoclonal antibodyCanine
GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2Anti-Bovine SNAP25 monoclonal antibodyBovine
GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2Anti-Equine SNAP25 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2; GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2;
GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2; GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2;
GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2; GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2;
GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2; GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2
Products NameAnti-SNAP25 monoclonal antibody
Target NameSNAP25
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-SNAP25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T71023-Ag-1Multi-species SNP25/ SNAP25/ CMS18 VLP (virus-like particle)
    ORF Viral VectorpGMLP004868human SNAP25 Lentivirus plasmid
    ORF Viral VectorvGMLP004868human SNAP25 Lentivirus particle

    Target information

    Target IDGM-T71023
    Target NameSNAP25
    Gene ID6616,20614,25012,574204,477158,101092511,540853,100051273
    Gene Symbol and SynonymsbA416N4.2,Bdr,CMS18,dJ1068F16.2,GENA70,RIC-4,RIC4,SEC9,SNAP,SNAP-25,SNAP-25a,SNAP-25B,SNAP25,sp,SUP
    Uniprot AccessionP60880,P60881,P60877,Q17QQ3
    Uniprot Entry NameSNP25_HUMAN,SNP25_MACMU,SNP25_RAT,SNP25_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000132639
    Target ClassificationN/A

    The target: SNAP25, gene name: SNAP25, also named as CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

    About Gmab

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.