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Anti-SNP25/ SNAP25/ CMS18 monoclonal antibody
Anti-SNP25/ SNAP25/ CMS18 antibody for FACS & in-vivo assay
Go to SNAP25/SNAP25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2 | Anti-Human SNAP25 monoclonal antibody | Human |
| GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2 | Anti-Rat SNAP25 monoclonal antibody | Rat |
| GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2 | Anti-Mouse SNAP25 monoclonal antibody | Mouse |
| GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SNAP25 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2 | Anti-Feline SNAP25 monoclonal antibody | Feline |
| GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2 | Anti-Canine SNAP25 monoclonal antibody | Canine |
| GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2 | Anti-Bovine SNAP25 monoclonal antibody | Bovine |
| GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 | Anti-Equine SNAP25 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2; GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2; GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2; GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2; GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2; GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2; GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2; GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 |
| Products Name | Anti-SNAP25 monoclonal antibody |
| Format | mab |
| Target Name | SNAP25 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SNAP25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SNP25/ SNAP25/ CMS18 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP004868 | human SNAP25 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004868 | human SNAP25 Lentivirus particle |
Target information
| Target ID | GM-T71023 |
| Target Name | SNAP25 |
| Gene ID | 6616,20614,25012,574204,477158,101092511,540853,100051273 |
| Gene Symbol and Synonyms | bA416N4.2,Bdr,CMS18,dJ1068F16.2,GENA70,RIC-4,RIC4,SEC9,SNAP,SNAP-25,SNAP-25a,SNAP-25B,SNAP25,sp,SUP |
| Uniprot Accession | P60880,P60881,P60877,Q17QQ3 |
| Uniprot Entry Name | SNP25_HUMAN,SNP25_MACMU,SNP25_RAT,SNP25_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000132639 |
| Target Classification | N/A |
The target: SNAP25, gene name: SNAP25, also named as CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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