Anti-SNP25/ SNAP25/ CMS18 monoclonal antibody
Anti-SNP25/ SNAP25/ CMS18 antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2 | Anti-Human SNAP25 monoclonal antibody | Human |
GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2 | Anti-Rat SNAP25 monoclonal antibody | Rat |
GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2 | Anti-Mouse SNAP25 monoclonal antibody | Mouse |
GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SNAP25 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2 | Anti-Feline SNAP25 monoclonal antibody | Feline |
GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2 | Anti-Canine SNAP25 monoclonal antibody | Canine |
GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2 | Anti-Bovine SNAP25 monoclonal antibody | Bovine |
GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 | Anti-Equine SNAP25 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2; GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2; GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2; GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2; GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2; GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2; GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2; GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 |
Products Name | Anti-SNAP25 monoclonal antibody |
Format | mab |
Target Name | SNAP25 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SNAP25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species SNP25/ SNAP25/ CMS18 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLP004868 | human SNAP25 Lentivirus plasmid |
ORF Viral Vector | vGMLP004868 | human SNAP25 Lentivirus particle |
Target information
Target ID | GM-T71023 |
Target Name | SNAP25 |
Gene ID | 6616,20614,25012,574204,477158,101092511,540853,100051273 |
Gene Symbol and Synonyms | bA416N4.2,Bdr,CMS18,dJ1068F16.2,GENA70,RIC-4,RIC4,SEC9,SNAP,SNAP-25,SNAP-25a,SNAP-25B,SNAP25,sp,SUP |
Uniprot Accession | P60880,P60881,P60877,Q17QQ3 |
Uniprot Entry Name | SNP25_HUMAN,SNP25_MACMU,SNP25_RAT,SNP25_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000132639 |
Target Classification | N/A |
The target: SNAP25, gene name: SNAP25, also named as CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.