- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
 |
 |
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Sample Application
Anti-SNP25/ SNAP25/ CMS18 monoclonal antibody
Anti-SNP25/ SNAP25/ CMS18 antibody for FACS & in-vivo assay
Go to SNAP25/SNAP25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
SDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2 | Anti-Human SNAP25 monoclonal antibody | Human |
| GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2 | Anti-Rat SNAP25 monoclonal antibody | Rat |
| GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2 | Anti-Mouse SNAP25 monoclonal antibody | Mouse |
| GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SNAP25 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2 | Anti-Feline SNAP25 monoclonal antibody | Feline |
| GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2 | Anti-Canine SNAP25 monoclonal antibody | Canine |
| GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2 | Anti-Bovine SNAP25 monoclonal antibody | Bovine |
| GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 | Anti-Equine SNAP25 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T71023-Ab-1/ GM-Tg-hg-T71023-Ab-2; GM-Tg-rg-T71023-Ab-1/ GM-Tg-rg-T71023-Ab-2; GM-Tg-mg-T71023-Ab-1/ GM-Tg-mg-T71023-Ab-2; GM-Tg-cynog-T71023-Ab-1/ GM-Tg-cynog-T71023-Ab-2; GM-Tg-felg-T71023-Ab-1/ GM-Tg-felg-T71023-Ab-2; GM-Tg-cang-T71023-Ab-1/ GM-Tg-cang-T71023-Ab-2; GM-Tg-bovg-T71023-Ab-1/ GM-Tg-bovg-T71023-Ab-2; GM-Tg-equg-T71023-Ab-1/ GM-Tg-equg-T71023-Ab-2 |
| Products Name | Anti-SNAP25 monoclonal antibody |
| Format | mab |
| Target Name | SNAP25 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SNAP25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T71023-Ag-1 | Multi-species SNP25/ SNAP25/ CMS18 VLP (virus-like particle) |
| ORF Viral Vector | pGMLP004868 | human SNAP25 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004868 | human SNAP25 Lentivirus particle |
Target information
| Target ID | GM-T71023 |
| Target Name | SNAP25 |
| Gene ID | 6616,20614,25012,574204,477158,101092511,540853,100051273 |
| Gene Symbol and Synonyms | bA416N4.2,Bdr,CMS18,dJ1068F16.2,GENA70,RIC-4,RIC4,SEC9,SNAP,SNAP-25,SNAP-25a,SNAP-25B,SNAP25,sp,SUP |
| Uniprot Accession | P60880,P60881,P60877,Q17QQ3 |
| Uniprot Entry Name | SNP25_HUMAN,SNP25_MACMU,SNP25_RAT,SNP25_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000132639 |
| Target Classification | N/A |
The target: SNAP25, gene name: SNAP25, also named as CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
