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Anti-MC4R monoclonal antibody
Anti-MC4R antibody for FACS & in-vivo assay
Go to MC4R/MC4R products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T72458-Ab-1/ GM-Tg-hg-T72458-Ab-2 | Anti-Human MC4R monoclonal antibody | Human |
| GM-Tg-rg-T72458-Ab-1/ GM-Tg-rg-T72458-Ab-2 | Anti-Rat MC4R monoclonal antibody | Rat |
| GM-Tg-mg-T72458-Ab-1/ GM-Tg-mg-T72458-Ab-2 | Anti-Mouse MC4R monoclonal antibody | Mouse |
| GM-Tg-cynog-T72458-Ab-1/ GM-Tg-cynog-T72458-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MC4R monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T72458-Ab-1/ GM-Tg-felg-T72458-Ab-2 | Anti-Feline MC4R monoclonal antibody | Feline |
| GM-Tg-cang-T72458-Ab-1/ GM-Tg-cang-T72458-Ab-2 | Anti-Canine MC4R monoclonal antibody | Canine |
| GM-Tg-bovg-T72458-Ab-1/ GM-Tg-bovg-T72458-Ab-2 | Anti-Bovine MC4R monoclonal antibody | Bovine |
| GM-Tg-equg-T72458-Ab-1/ GM-Tg-equg-T72458-Ab-2 | Anti-Equine MC4R monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T72458-Ab-1/ GM-Tg-hg-T72458-Ab-2; GM-Tg-rg-T72458-Ab-1/ GM-Tg-rg-T72458-Ab-2; GM-Tg-mg-T72458-Ab-1/ GM-Tg-mg-T72458-Ab-2; GM-Tg-cynog-T72458-Ab-1/ GM-Tg-cynog-T72458-Ab-2; GM-Tg-felg-T72458-Ab-1/ GM-Tg-felg-T72458-Ab-2; GM-Tg-cang-T72458-Ab-1/ GM-Tg-cang-T72458-Ab-2; GM-Tg-bovg-T72458-Ab-1/ GM-Tg-bovg-T72458-Ab-2; GM-Tg-equg-T72458-Ab-1/ GM-Tg-equg-T72458-Ab-2 |
| Products Name | Anti-MC4R monoclonal antibody |
| Format | mab |
| Target Name | MC4R |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MC4R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MC4R VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLV000201 | human MC4R Lentivirus particle |
| ORF Viral Vector | pGMLV000201 | human MC4R Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000414 | mouse Mc4r Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000414 | mouse Mc4r Lentivirus particle |
Target information
| Target ID | GM-T72458 |
| Target Name | MC4R |
| Gene ID | 4160,17202,25635,698596,483961,101081334,281300,100050469 |
| Gene Symbol and Synonyms | BMIQ20,Mc4-r,MC4R,Pkcp |
| Uniprot Accession | P32245,P70596,Q9GLJ8 |
| Uniprot Entry Name | MC4R_HUMAN,MC4R_RAT,MC4R_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000166603 |
| Target Classification | GPCR |
The target: MC4R, gene name: MC4R, also named as . The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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