Anti-SV2A/ SV2 monoclonal antibody

Anti-SV2A/ SV2 antibody for FACS & in-vivo assay

Target products collectionGo to SV2A/SV2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T73676-Ab-1/ GM-Tg-hg-T73676-Ab-2Anti-Human SV2A monoclonal antibodyHuman
GM-Tg-rg-T73676-Ab-1/ GM-Tg-rg-T73676-Ab-2Anti-Rat SV2A monoclonal antibodyRat
GM-Tg-mg-T73676-Ab-1/ GM-Tg-mg-T73676-Ab-2Anti-Mouse SV2A monoclonal antibodyMouse
GM-Tg-cynog-T73676-Ab-1/ GM-Tg-cynog-T73676-Ab-2Anti-Cynomolgus/ Rhesus macaque SV2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T73676-Ab-1/ GM-Tg-felg-T73676-Ab-2Anti-Feline SV2A monoclonal antibodyFeline
GM-Tg-cang-T73676-Ab-1/ GM-Tg-cang-T73676-Ab-2Anti-Canine SV2A monoclonal antibodyCanine
GM-Tg-bovg-T73676-Ab-1/ GM-Tg-bovg-T73676-Ab-2Anti-Bovine SV2A monoclonal antibodyBovine
GM-Tg-equg-T73676-Ab-1/ GM-Tg-equg-T73676-Ab-2Anti-Equine SV2A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T73676-Ab-1/ GM-Tg-hg-T73676-Ab-2; GM-Tg-rg-T73676-Ab-1/ GM-Tg-rg-T73676-Ab-2;
GM-Tg-mg-T73676-Ab-1/ GM-Tg-mg-T73676-Ab-2; GM-Tg-cynog-T73676-Ab-1/ GM-Tg-cynog-T73676-Ab-2;
GM-Tg-felg-T73676-Ab-1/ GM-Tg-felg-T73676-Ab-2; GM-Tg-cang-T73676-Ab-1/ GM-Tg-cang-T73676-Ab-2;
GM-Tg-bovg-T73676-Ab-1/ GM-Tg-bovg-T73676-Ab-2; GM-Tg-equg-T73676-Ab-1/ GM-Tg-equg-T73676-Ab-2
Products NameAnti-SV2A monoclonal antibody
Formatmab
Target NameSV2A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SV2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SV2A/ SV2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T73676
    Target NameSV2A
    Gene ID9900,64051,117559,715018,100855661,101081564,280936,100054302
    Gene Symbol and SynonymsmKIAA0736,SLC22B1,SV2,SV2A
    Uniprot AccessionQ7L0J3,Q02563,Q29397
    Uniprot Entry NameSV2A_HUMAN,SV2A_RAT,SV2A_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000159164
    Target ClassificationN/A

    The target: SV2A, gene name: SV2A, also named as SV2. The protein encoded by this gene is one of three related synaptic vesicle proteins. The encoded protein may interact with synaptotagmin to enhance low frequency neurotransmission in quiescent neurons. [provided by RefSeq, Jun 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.