Anti-FABP1 monoclonal antibody
Pre-made anti-FABP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T73712-Ab-1/ GM-Tg-hg-T73712-Ab-2 | Anti-Human FABP1 monoclonal antibody | Human |
GM-Tg-rg-T73712-Ab-1/ GM-Tg-rg-T73712-Ab-2 | Anti-Rat FABP1 monoclonal antibody | Rat |
GM-Tg-mg-T73712-Ab-1/ GM-Tg-mg-T73712-Ab-2 | Anti-Mouse FABP1 monoclonal antibody | Mouse |
GM-Tg-cynog-T73712-Ab-1/ GM-Tg-cynog-T73712-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FABP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T73712-Ab-1/ GM-Tg-felg-T73712-Ab-2 | Anti-Feline FABP1 monoclonal antibody | Feline |
GM-Tg-cang-T73712-Ab-1/ GM-Tg-cang-T73712-Ab-2 | Anti-Canine FABP1 monoclonal antibody | Canine |
GM-Tg-bovg-T73712-Ab-1/ GM-Tg-bovg-T73712-Ab-2 | Anti-Bovine FABP1 monoclonal antibody | Bovine |
GM-Tg-equg-T73712-Ab-1/ GM-Tg-equg-T73712-Ab-2 | Anti-Equine FABP1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T73712-Ab-1/ GM-Tg-hg-T73712-Ab-2; GM-Tg-rg-T73712-Ab-1/ GM-Tg-rg-T73712-Ab-2; GM-Tg-mg-T73712-Ab-1/ GM-Tg-mg-T73712-Ab-2; GM-Tg-cynog-T73712-Ab-1/ GM-Tg-cynog-T73712-Ab-2; GM-Tg-felg-T73712-Ab-1/ GM-Tg-felg-T73712-Ab-2; GM-Tg-cang-T73712-Ab-1/ GM-Tg-cang-T73712-Ab-2; GM-Tg-bovg-T73712-Ab-1/ GM-Tg-bovg-T73712-Ab-2; GM-Tg-equg-T73712-Ab-1/ GM-Tg-equg-T73712-Ab-2 |
Products Name | Anti-FABP1 monoclonal antibody |
Format | mab |
Target Name | FABP1 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-FABP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T73712-Ag-1 | Recombinant multi-species FABPL/ FABP1/ L-FABP protein |
ORF Viral Vector | vGMLP002096 | human FABP1 Lentivirus particle |
ORF Viral Vector | pGMLP002096 | human FABP1 Lentivirus plasmid |
ORF Viral Vector | pGMLPm000083 | mouse Fabp1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000083 | mouse Fabp1 Lentivirus particle |
Target information
Target ID | GM-T73712 |
Target Name | FABP1 |
Gene ID | 2168,14080,24360,699776,403619,101095488,327700,100052746 |
Gene Symbol and Synonyms | FABP,FABP1,FABPL,Fabplg,L-FABP,p14,SCP,SCP. |
Uniprot Accession | P07148,P02692,P80425 |
Uniprot Entry Name | FABPL_HUMAN,FABPL_RAT,FABPL_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Injury to Kidney, Acute kidney failure, Chronic Kidney Disease, Chronic nephritic syndrome, Complications of kidney transplant, Contrast - Induced Nephropathy, Coronary artery disease, Delayed Graft Function, Other diseases of intestines (K55-K64), Other obstructive and reflux uropathy, Tubulo-interstitial nephropathy in systemic lupus erythematosus, Type 1 diabetes mellitus, Type 2 diabetes mellitus with diabetic chronic kidney disease, Type 2 diabetes mellitus with diabetic nephropathy, Diabetes mellitus |
Gene Ensembl | ENSG00000163586 |
Target Classification | N/A |
The target: FABP1, gene name: FABP1, also named as FABPL, L-FABP. This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.