Anti-TA2R/ TBXA2R/ BDPLT13 monoclonal antibody

Anti-TA2R/ TBXA2R/ BDPLT13 antibody for FACS & in-vivo assay

Target products collectionGo to TBXA2R/TBXA2R products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T76198-Ab-1/ GM-Tg-hg-T76198-Ab-2Anti-Human TBXA2R monoclonal antibodyHuman
GM-Tg-rg-T76198-Ab-1/ GM-Tg-rg-T76198-Ab-2Anti-Rat TBXA2R monoclonal antibodyRat
GM-Tg-mg-T76198-Ab-1/ GM-Tg-mg-T76198-Ab-2Anti-Mouse TBXA2R monoclonal antibodyMouse
GM-Tg-cynog-T76198-Ab-1/ GM-Tg-cynog-T76198-Ab-2Anti-Cynomolgus/ Rhesus macaque TBXA2R monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T76198-Ab-1/ GM-Tg-felg-T76198-Ab-2Anti-Feline TBXA2R monoclonal antibodyFeline
GM-Tg-cang-T76198-Ab-1/ GM-Tg-cang-T76198-Ab-2Anti-Canine TBXA2R monoclonal antibodyCanine
GM-Tg-bovg-T76198-Ab-1/ GM-Tg-bovg-T76198-Ab-2Anti-Bovine TBXA2R monoclonal antibodyBovine
GM-Tg-equg-T76198-Ab-1/ GM-Tg-equg-T76198-Ab-2Anti-Equine TBXA2R monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T76198-Ab-1/ GM-Tg-hg-T76198-Ab-2; GM-Tg-rg-T76198-Ab-1/ GM-Tg-rg-T76198-Ab-2;
GM-Tg-mg-T76198-Ab-1/ GM-Tg-mg-T76198-Ab-2; GM-Tg-cynog-T76198-Ab-1/ GM-Tg-cynog-T76198-Ab-2;
GM-Tg-felg-T76198-Ab-1/ GM-Tg-felg-T76198-Ab-2; GM-Tg-cang-T76198-Ab-1/ GM-Tg-cang-T76198-Ab-2;
GM-Tg-bovg-T76198-Ab-1/ GM-Tg-bovg-T76198-Ab-2; GM-Tg-equg-T76198-Ab-1/ GM-Tg-equg-T76198-Ab-2
Products NameAnti-TBXA2R monoclonal antibody
Formatmab
Target NameTBXA2R
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TBXA2R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TA2R/ TBXA2R/ BDPLT13 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm002779mouse Tbxa2r Lentivirus plasmid
    ORF Viral VectorvGMLPm002779mouse Tbxa2r Lentivirus particle


    Target information

    Target IDGM-T76198
    Target NameTBXA2R
    Gene ID6915,21390,24816,721732,485056,101089081,538783,111774174
    Gene Symbol and SynonymsBDPLT13,TBXA2R,TP,TXA2-R
    Uniprot AccessionP21731,P34978,Q95125
    Uniprot Entry NameTA2R_HUMAN,TA2R_RAT,TA2R_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseProstate Cancer
    Gene EnsemblENSG00000006638
    Target ClassificationGPCR

    The target: TBXA2R, gene name: TBXA2R, also named as BDPLT13, TXA2-R. This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.