Anti-PGD monoclonal antibody

Pre-made anti-PGD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PGD/PGD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T76497-Ab-1/ GM-Tg-hg-T76497-Ab-2Anti-Human PGD monoclonal antibodyHuman
GM-Tg-rg-T76497-Ab-1/ GM-Tg-rg-T76497-Ab-2Anti-Rat PGD monoclonal antibodyRat
GM-Tg-mg-T76497-Ab-1/ GM-Tg-mg-T76497-Ab-2Anti-Mouse PGD monoclonal antibodyMouse
GM-Tg-cynog-T76497-Ab-1/ GM-Tg-cynog-T76497-Ab-2Anti-Cynomolgus/ Rhesus macaque PGD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T76497-Ab-1/ GM-Tg-felg-T76497-Ab-2Anti-Feline PGD monoclonal antibodyFeline
GM-Tg-cang-T76497-Ab-1/ GM-Tg-cang-T76497-Ab-2Anti-Canine PGD monoclonal antibodyCanine
GM-Tg-bovg-T76497-Ab-1/ GM-Tg-bovg-T76497-Ab-2Anti-Bovine PGD monoclonal antibodyBovine
GM-Tg-equg-T76497-Ab-1/ GM-Tg-equg-T76497-Ab-2Anti-Equine PGD monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T76497-Ab-1/ GM-Tg-hg-T76497-Ab-2; GM-Tg-rg-T76497-Ab-1/ GM-Tg-rg-T76497-Ab-2;
GM-Tg-mg-T76497-Ab-1/ GM-Tg-mg-T76497-Ab-2; GM-Tg-cynog-T76497-Ab-1/ GM-Tg-cynog-T76497-Ab-2;
GM-Tg-felg-T76497-Ab-1/ GM-Tg-felg-T76497-Ab-2; GM-Tg-cang-T76497-Ab-1/ GM-Tg-cang-T76497-Ab-2;
GM-Tg-bovg-T76497-Ab-1/ GM-Tg-bovg-T76497-Ab-2; GM-Tg-equg-T76497-Ab-1/ GM-Tg-equg-T76497-Ab-2
Products NameAnti-PGD monoclonal antibody
Formatmab
Target NamePGD
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PGD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T76497-Ag-1Recombinant multi-species 6PGD/ PGD protein
    ORF Viral VectorvGMLP002159human PGD Lentivirus particle
    ORF Viral VectorpGMLP002159human PGD Lentivirus plasmid
    ORF Viral VectorpGMLPm001360mouse Pgd Lentivirus plasmid
    ORF Viral VectorvGMLPm001360mouse Pgd Lentivirus particle


    Target information

    Target IDGM-T76497
    Target NamePGD
    Gene ID5226,110208,100360180,107000661,478236,101096246,514939,100146298
    Gene Symbol and Synonyms0610042A05Rik,6PGD,Cc2-27,PGD
    Uniprot AccessionP52209,P85968
    Uniprot Entry Name6PGD_HUMAN,6PGD_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000142657
    Target ClassificationN/A

    The target: PGD, gene name: PGD, also named as 6PGD. 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.