Anti-GSK-3A monoclonal antibody

Pre-made anti-GSK-3A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GSK-3A/GSK3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T76910-Ab-1/ GM-Tg-hg-T76910-Ab-2Anti-Human GSK-3A/GSK3A monoclonal antibodyHuman
GM-Tg-rg-T76910-Ab-1/ GM-Tg-rg-T76910-Ab-2Anti-Rat GSK-3A/GSK3A monoclonal antibodyRat
GM-Tg-mg-T76910-Ab-1/ GM-Tg-mg-T76910-Ab-2Anti-Mouse GSK-3A/GSK3A monoclonal antibodyMouse
GM-Tg-cynog-T76910-Ab-1/ GM-Tg-cynog-T76910-Ab-2Anti-Cynomolgus/ Rhesus macaque GSK-3A/GSK3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T76910-Ab-1/ GM-Tg-felg-T76910-Ab-2Anti-Feline GSK-3A/GSK3A monoclonal antibodyFeline
GM-Tg-cang-T76910-Ab-1/ GM-Tg-cang-T76910-Ab-2Anti-Canine GSK-3A/GSK3A monoclonal antibodyCanine
GM-Tg-bovg-T76910-Ab-1/ GM-Tg-bovg-T76910-Ab-2Anti-Bovine GSK-3A/GSK3A monoclonal antibodyBovine
GM-Tg-equg-T76910-Ab-1/ GM-Tg-equg-T76910-Ab-2Anti-Equine GSK-3A/GSK3A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T76910-Ab-1/ GM-Tg-hg-T76910-Ab-2; GM-Tg-rg-T76910-Ab-1/ GM-Tg-rg-T76910-Ab-2;
GM-Tg-mg-T76910-Ab-1/ GM-Tg-mg-T76910-Ab-2; GM-Tg-cynog-T76910-Ab-1/ GM-Tg-cynog-T76910-Ab-2;
GM-Tg-felg-T76910-Ab-1/ GM-Tg-felg-T76910-Ab-2; GM-Tg-cang-T76910-Ab-1/ GM-Tg-cang-T76910-Ab-2;
GM-Tg-bovg-T76910-Ab-1/ GM-Tg-bovg-T76910-Ab-2; GM-Tg-equg-T76910-Ab-1/ GM-Tg-equg-T76910-Ab-2
Products NameAnti-GSK-3A/GSK3A monoclonal antibody
Formatmab
Target NameGSK-3A
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GSK-3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T76910-Ag-1Recombinant multi-species GSK3A/ GSK-3A protein
    ORF Viral VectorpGMLPm002524mouse Gsk3a Lentivirus plasmid
    ORF Viral VectorvGMLPm002524mouse Gsk3a Lentivirus particle


    Target information

    Target IDGM-T76910
    Target NameGSK-3A
    Gene ID2931,606496,50686,707037,484476,101084151,536561,100069693
    Gene Symbol and Synonyms2700086H06Rik,GSK3A
    Uniprot AccessionP49840,P18265
    Uniprot Entry NameGSK3A_HUMAN,GSK3A_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000105723
    Target ClassificationKinase

    The target: GSK-3A, gene name: GSK3A, also named as . This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.