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Anti-PRDX5 monoclonal antibody
Pre-made anti-PRDX5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PRDX5/PRDX5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T77009-Ab-1/ GM-Tg-hg-T77009-Ab-2 | Anti-Human PRDX5 monoclonal antibody | Human |
| GM-Tg-rg-T77009-Ab-1/ GM-Tg-rg-T77009-Ab-2 | Anti-Rat PRDX5 monoclonal antibody | Rat |
| GM-Tg-mg-T77009-Ab-1/ GM-Tg-mg-T77009-Ab-2 | Anti-Mouse PRDX5 monoclonal antibody | Mouse |
| GM-Tg-cynog-T77009-Ab-1/ GM-Tg-cynog-T77009-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRDX5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T77009-Ab-1/ GM-Tg-felg-T77009-Ab-2 | Anti-Feline PRDX5 monoclonal antibody | Feline |
| GM-Tg-cang-T77009-Ab-1/ GM-Tg-cang-T77009-Ab-2 | Anti-Canine PRDX5 monoclonal antibody | Canine |
| GM-Tg-bovg-T77009-Ab-1/ GM-Tg-bovg-T77009-Ab-2 | Anti-Bovine PRDX5 monoclonal antibody | Bovine |
| GM-Tg-equg-T77009-Ab-1/ GM-Tg-equg-T77009-Ab-2 | Anti-Equine PRDX5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T77009-Ab-1/ GM-Tg-hg-T77009-Ab-2; GM-Tg-rg-T77009-Ab-1/ GM-Tg-rg-T77009-Ab-2; GM-Tg-mg-T77009-Ab-1/ GM-Tg-mg-T77009-Ab-2; GM-Tg-cynog-T77009-Ab-1/ GM-Tg-cynog-T77009-Ab-2; GM-Tg-felg-T77009-Ab-1/ GM-Tg-felg-T77009-Ab-2; GM-Tg-cang-T77009-Ab-1/ GM-Tg-cang-T77009-Ab-2; GM-Tg-bovg-T77009-Ab-1/ GM-Tg-bovg-T77009-Ab-2; GM-Tg-equg-T77009-Ab-1/ GM-Tg-equg-T77009-Ab-2 |
| Products Name | Anti-PRDX5 monoclonal antibody |
| Format | mab |
| Target Name | PRDX5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PRDX5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T77009-Ag-1 | Recombinant multi-species PRDX5/ ACR1/ AOEB166 protein |
| ORF Viral Vector | pGMLP002999 | human PRDX5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002999 | human PRDX5 Lentivirus particle |
| ORF Viral Vector | pGMLPm001567 | mouse Prdx5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001567 | mouse Prdx5 Lentivirus particle |
Target information
| Target ID | GM-T77009 |
| Target Name | PRDX5 |
| Gene ID | 25824,54683,113898,719764,476032,101093462,282885,100055657 |
| Gene Symbol and Synonyms | ACR1,AOEB166,AOPP,B166,HEL-S-55,PLP,PMP20,PRDX5,PRDX6,Prx V,prx-V,PRXV,SBBI10 |
| Uniprot Accession | P30044,Q9R063,Q9BGI1 |
| Uniprot Entry Name | PRDX5_HUMAN,PRDX5_RAT,PRDX5_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000126432 |
| Target Classification | N/A |
The target: PRDX5, gene name: PRDX5, also named as ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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