Anti-ASRGL1 monoclonal antibody

Pre-made anti-ASRGL1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ASRGL1/ASRGL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T78277-Ab-1/ GM-Tg-hg-T78277-Ab-2Anti-Human ASRGL1 monoclonal antibodyHuman
GM-Tg-rg-T78277-Ab-1/ GM-Tg-rg-T78277-Ab-2Anti-Rat ASRGL1 monoclonal antibodyRat
GM-Tg-mg-T78277-Ab-1/ GM-Tg-mg-T78277-Ab-2Anti-Mouse ASRGL1 monoclonal antibodyMouse
GM-Tg-cynog-T78277-Ab-1/ GM-Tg-cynog-T78277-Ab-2Anti-Cynomolgus/ Rhesus macaque ASRGL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T78277-Ab-1/ GM-Tg-felg-T78277-Ab-2Anti-Feline ASRGL1 monoclonal antibodyFeline
GM-Tg-cang-T78277-Ab-1/ GM-Tg-cang-T78277-Ab-2Anti-Canine ASRGL1 monoclonal antibodyCanine
GM-Tg-bovg-T78277-Ab-1/ GM-Tg-bovg-T78277-Ab-2Anti-Bovine ASRGL1 monoclonal antibodyBovine
GM-Tg-equg-T78277-Ab-1/ GM-Tg-equg-T78277-Ab-2Anti-Equine ASRGL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T78277-Ab-1/ GM-Tg-hg-T78277-Ab-2; GM-Tg-rg-T78277-Ab-1/ GM-Tg-rg-T78277-Ab-2;
GM-Tg-mg-T78277-Ab-1/ GM-Tg-mg-T78277-Ab-2; GM-Tg-cynog-T78277-Ab-1/ GM-Tg-cynog-T78277-Ab-2;
GM-Tg-felg-T78277-Ab-1/ GM-Tg-felg-T78277-Ab-2; GM-Tg-cang-T78277-Ab-1/ GM-Tg-cang-T78277-Ab-2;
GM-Tg-bovg-T78277-Ab-1/ GM-Tg-bovg-T78277-Ab-2; GM-Tg-equg-T78277-Ab-1/ GM-Tg-equg-T78277-Ab-2
Products NameAnti-ASRGL1 monoclonal antibody
Formatmab
Target NameASRGL1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ASRGL1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T78277-Ag-1Recombinant multi-species ASGL1/ ASRGL1/ ALP protein
    ORF Viral VectorvGMLP000944human ASRGL1 Lentivirus particle
    ORF Viral VectorpGMLP000944human ASRGL1 Lentivirus plasmid
    ORF Viral VectorpGMLPm000825mouse Asrgl1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000825mouse Asrgl1 Lentivirus particle


    Target information

    Target IDGM-T78277
    Target NameASRGL1
    Gene ID80150,66514,246307,718871,483789,101087268,767970
    Gene Symbol and Synonyms2410004D18Rik,ALP,ALP1,ASRGL1,CRASH,Gliap,Hiob2
    Uniprot AccessionQ7L266,Q8VI04,Q32LE5
    Uniprot Entry NameASGL1_HUMAN,ASGL1_RAT,ASGL1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000162174
    Target ClassificationN/A

    The target: ASRGL1, gene name: ASRGL1, also named as ALP, ALP1, CRASH. Enables asparaginase activity and beta-aspartyl-peptidase activity. Involved in asparagine catabolic process via L-aspartate. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.