- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-NEK6 monoclonal antibody
Pre-made anti-NEK6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NEK6/NEK6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T78992-Ab-1/ GM-Tg-hg-T78992-Ab-2 | Anti-Human NEK6 monoclonal antibody | Human |
| GM-Tg-rg-T78992-Ab-1/ GM-Tg-rg-T78992-Ab-2 | Anti-Rat NEK6 monoclonal antibody | Rat |
| GM-Tg-mg-T78992-Ab-1/ GM-Tg-mg-T78992-Ab-2 | Anti-Mouse NEK6 monoclonal antibody | Mouse |
| GM-Tg-cynog-T78992-Ab-1/ GM-Tg-cynog-T78992-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NEK6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T78992-Ab-1/ GM-Tg-felg-T78992-Ab-2 | Anti-Feline NEK6 monoclonal antibody | Feline |
| GM-Tg-cang-T78992-Ab-1/ GM-Tg-cang-T78992-Ab-2 | Anti-Canine NEK6 monoclonal antibody | Canine |
| GM-Tg-bovg-T78992-Ab-1/ GM-Tg-bovg-T78992-Ab-2 | Anti-Bovine NEK6 monoclonal antibody | Bovine |
| GM-Tg-equg-T78992-Ab-1/ GM-Tg-equg-T78992-Ab-2 | Anti-Equine NEK6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T78992-Ab-1/ GM-Tg-hg-T78992-Ab-2; GM-Tg-rg-T78992-Ab-1/ GM-Tg-rg-T78992-Ab-2; GM-Tg-mg-T78992-Ab-1/ GM-Tg-mg-T78992-Ab-2; GM-Tg-cynog-T78992-Ab-1/ GM-Tg-cynog-T78992-Ab-2; GM-Tg-felg-T78992-Ab-1/ GM-Tg-felg-T78992-Ab-2; GM-Tg-cang-T78992-Ab-1/ GM-Tg-cang-T78992-Ab-2; GM-Tg-bovg-T78992-Ab-1/ GM-Tg-bovg-T78992-Ab-2; GM-Tg-equg-T78992-Ab-1/ GM-Tg-equg-T78992-Ab-2 |
| Products Name | Anti-NEK6 monoclonal antibody |
| Format | mab |
| Target Name | NEK6 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NEK6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T78992-Ag-1 | Recombinant multi-species NEK6/ SID6-1512 protein |
Target information
| Target ID | GM-T78992 |
| Target Name | NEK6 |
| Gene ID | 10783,59126,360161,100427402,609003,101080747,515816,100071002 |
| Gene Symbol and Synonyms | 1300007C09Rik,NEK6,SID6-1512 |
| Uniprot Accession | Q9HC98,P59895 |
| Uniprot Entry Name | NEK6_HUMAN,NEK6_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000119408 |
| Target Classification | Kinase |
The target: NEK6, gene name: NEK6, also named as SID6-1512. The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
