Anti-™SB4X monoclonal antibody

Pre-made anti-™SB4X monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™SB4X/™SB4X products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T85005-Ab-1/ GM-Tg-hg-T85005-Ab-2Anti-Human ™SB4X monoclonal antibodyHuman
GM-Tg-rg-T85005-Ab-1/ GM-Tg-rg-T85005-Ab-2Anti-Rat ™SB4X monoclonal antibodyRat
GM-Tg-mg-T85005-Ab-1/ GM-Tg-mg-T85005-Ab-2Anti-Mouse ™SB4X monoclonal antibodyMouse
GM-Tg-cynog-T85005-Ab-1/ GM-Tg-cynog-T85005-Ab-2Anti-Cynomolgus/ Rhesus macaque ™SB4X monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T85005-Ab-1/ GM-Tg-felg-T85005-Ab-2Anti-Feline ™SB4X monoclonal antibodyFeline
GM-Tg-cang-T85005-Ab-1/ GM-Tg-cang-T85005-Ab-2Anti-Canine ™SB4X monoclonal antibodyCanine
GM-Tg-bovg-T85005-Ab-1/ GM-Tg-bovg-T85005-Ab-2Anti-Bovine ™SB4X monoclonal antibodyBovine
GM-Tg-equg-T85005-Ab-1/ GM-Tg-equg-T85005-Ab-2Anti-Equine ™SB4X monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T85005-Ab-1/ GM-Tg-hg-T85005-Ab-2; GM-Tg-rg-T85005-Ab-1/ GM-Tg-rg-T85005-Ab-2;
GM-Tg-mg-T85005-Ab-1/ GM-Tg-mg-T85005-Ab-2; GM-Tg-cynog-T85005-Ab-1/ GM-Tg-cynog-T85005-Ab-2;
GM-Tg-felg-T85005-Ab-1/ GM-Tg-felg-T85005-Ab-2; GM-Tg-cang-T85005-Ab-1/ GM-Tg-cang-T85005-Ab-2;
GM-Tg-bovg-T85005-Ab-1/ GM-Tg-bovg-T85005-Ab-2; GM-Tg-equg-T85005-Ab-1/ GM-Tg-equg-T85005-Ab-2
Products NameAnti-™SB4X monoclonal antibody
Formatmab
Target Name™SB4X
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™SB4X monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T85005-Ag-1Recombinant multi-species TYB4/ ™SB4X/ FX protein
    ORF Viral VectorvGMLP003137human ™SB4X Lentivirus particle
    ORF Viral VectorpGMLP003137human ™SB4X Lentivirus plasmid
    ORF Viral VectorvGMLV000075human ™SB4X Lentivirus particle
    ORF Viral VectorpGMLV000075human ™SB4X Lentivirus plasmid
    ORF Viral VectorpGMLPm001871mouse Tmsb4x Lentivirus plasmid
    ORF Viral VectorvGMLPm001871mouse Tmsb4x Lentivirus particle


    Target information

    Target IDGM-T85005
    Target Name™SB4X
    Gene ID7114,19241,81814,710959,100684977,101088815,282386,100034015
    Gene Symbol and SynonymsFX,P™B4,Tb4,TB4X,Tbeta4,THYB4,™SB4,™SB4X
    Uniprot AccessionP62328,P62329,P62327
    Uniprot Entry NameTYB4_HUMAN,TYB4_RAT,TYB4_HORSE
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000205542
    Target ClassificationN/A

    The target: ™SB4X, gene name: ™SB4X, also named as FX, P™B4, TB4X, ™SB4. This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.