Anti-SRC/ ASV1/ THC6 monoclonal antibody

Anti-SRC/ ASV1/ THC6 antibody for FACS & in-vivo assay

Target products collectionGo to SRC/SRC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T85943-Ab-1/ GM-Tg-hg-T85943-Ab-2Anti-Human SRC monoclonal antibodyHuman
GM-Tg-rg-T85943-Ab-1/ GM-Tg-rg-T85943-Ab-2Anti-Rat SRC monoclonal antibodyRat
GM-Tg-mg-T85943-Ab-1/ GM-Tg-mg-T85943-Ab-2Anti-Mouse SRC monoclonal antibodyMouse
GM-Tg-cynog-T85943-Ab-1/ GM-Tg-cynog-T85943-Ab-2Anti-Cynomolgus/ Rhesus macaque SRC monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T85943-Ab-1/ GM-Tg-felg-T85943-Ab-2Anti-Feline SRC monoclonal antibodyFeline
GM-Tg-cang-T85943-Ab-1/ GM-Tg-cang-T85943-Ab-2Anti-Canine SRC monoclonal antibodyCanine
GM-Tg-bovg-T85943-Ab-1/ GM-Tg-bovg-T85943-Ab-2Anti-Bovine SRC monoclonal antibodyBovine
GM-Tg-equg-T85943-Ab-1/ GM-Tg-equg-T85943-Ab-2Anti-Equine SRC monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T85943-Ab-1/ GM-Tg-hg-T85943-Ab-2; GM-Tg-rg-T85943-Ab-1/ GM-Tg-rg-T85943-Ab-2;
GM-Tg-mg-T85943-Ab-1/ GM-Tg-mg-T85943-Ab-2; GM-Tg-cynog-T85943-Ab-1/ GM-Tg-cynog-T85943-Ab-2;
GM-Tg-felg-T85943-Ab-1/ GM-Tg-felg-T85943-Ab-2; GM-Tg-cang-T85943-Ab-1/ GM-Tg-cang-T85943-Ab-2;
GM-Tg-bovg-T85943-Ab-1/ GM-Tg-bovg-T85943-Ab-2; GM-Tg-equg-T85943-Ab-1/ GM-Tg-equg-T85943-Ab-2
Products NameAnti-SRC monoclonal antibody
Target NameSRC
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-SRC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SRC/ ASV1/ THC6 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLV000836human SRC Lentivirus plasmid
    ORF Viral VectorvGMLV000836human SRC Lentivirus particle
    ORF Viral VectorpGMLPm005033mouse Src Lentivirus plasmid
    ORF Viral VectorvGMLPm005033mouse Src Lentivirus particle

    Target information

    Target IDGM-T85943
    Target NameSRC
    Gene ID6714,20779,83805,701057,485864,101100378,535742,100069870
    Gene Symbol and SynonymsASV,c-SRC,p60-Src,pp60c-src,SRC,SRC1,THC6
    Uniprot AccessionP12931,Q9WUD9
    Uniprot Entry NameSRC_HUMAN,SRC_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000197122
    Target ClassificationKinase, Tumor-associated antigen (TAA)

    The target: SRC, gene name: SRC, also named as ASV1, THC6, c-SRC, p60-Src, SRC. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.