Anti-GART monoclonal antibody

Pre-made anti-GART monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GART/GART products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T89918-Ab-1/ GM-Tg-hg-T89918-Ab-2Anti-Human GART monoclonal antibodyHuman
GM-Tg-rg-T89918-Ab-1/ GM-Tg-rg-T89918-Ab-2Anti-Rat GART monoclonal antibodyRat
GM-Tg-mg-T89918-Ab-1/ GM-Tg-mg-T89918-Ab-2Anti-Mouse GART monoclonal antibodyMouse
GM-Tg-cynog-T89918-Ab-1/ GM-Tg-cynog-T89918-Ab-2Anti-Cynomolgus/ Rhesus macaque GART monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T89918-Ab-1/ GM-Tg-felg-T89918-Ab-2Anti-Feline GART monoclonal antibodyFeline
GM-Tg-cang-T89918-Ab-1/ GM-Tg-cang-T89918-Ab-2Anti-Canine GART monoclonal antibodyCanine
GM-Tg-bovg-T89918-Ab-1/ GM-Tg-bovg-T89918-Ab-2Anti-Bovine GART monoclonal antibodyBovine
GM-Tg-equg-T89918-Ab-1/ GM-Tg-equg-T89918-Ab-2Anti-Equine GART monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T89918-Ab-1/ GM-Tg-hg-T89918-Ab-2; GM-Tg-rg-T89918-Ab-1/ GM-Tg-rg-T89918-Ab-2;
GM-Tg-mg-T89918-Ab-1/ GM-Tg-mg-T89918-Ab-2; GM-Tg-cynog-T89918-Ab-1/ GM-Tg-cynog-T89918-Ab-2;
GM-Tg-felg-T89918-Ab-1/ GM-Tg-felg-T89918-Ab-2; GM-Tg-cang-T89918-Ab-1/ GM-Tg-cang-T89918-Ab-2;
GM-Tg-bovg-T89918-Ab-1/ GM-Tg-bovg-T89918-Ab-2; GM-Tg-equg-T89918-Ab-1/ GM-Tg-equg-T89918-Ab-2
Products NameAnti-GART monoclonal antibody
Formatmab
Target NameGART
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GART monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T89918-Ag-1Recombinant multi-species PUR2/ GART/ AIRS protein


    Target information

    Target IDGM-T89918
    Target NameGART
    Gene ID2618,14450,288259,704926,487740,101087772,281183,100052316
    Gene Symbol and SynonymsAIRS,Gaps,GARS,GART,GARTF,LOC487740,PAIS,PGFT,PRGS
    Uniprot AccessionP22102,Q59A32
    Uniprot Entry NamePUR2_HUMAN,PUR2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000159131
    Target ClassificationN/A

    The target: GART, gene name: GART, also named as AIRS, GARSF, PAIS, PGFT, PRGS, GART. The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.