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Anti-SMS/ SST/ SMST functional antibody
Anti-SMS/ SST/ SMST functional antibody for cell culture, ELISA & in-vivo assay
Go to SST/SST products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T95479-Ab-1/ GM-Tg-hg-T95479-Ab-2 | Anti-Human SST monoclonal antibody | Human |
| GM-Tg-rg-T95479-Ab-1/ GM-Tg-rg-T95479-Ab-2 | Anti-Rat SST monoclonal antibody | Rat |
| GM-Tg-mg-T95479-Ab-1/ GM-Tg-mg-T95479-Ab-2 | Anti-Mouse SST monoclonal antibody | Mouse |
| GM-Tg-cynog-T95479-Ab-1/ GM-Tg-cynog-T95479-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SST monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T95479-Ab-1/ GM-Tg-felg-T95479-Ab-2 | Anti-Feline SST monoclonal antibody | Feline |
| GM-Tg-cang-T95479-Ab-1/ GM-Tg-cang-T95479-Ab-2 | Anti-Canine SST monoclonal antibody | Canine |
| GM-Tg-bovg-T95479-Ab-1/ GM-Tg-bovg-T95479-Ab-2 | Anti-Bovine SST monoclonal antibody | Bovine |
| GM-Tg-equg-T95479-Ab-1/ GM-Tg-equg-T95479-Ab-2 | Anti-Equine SST monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T95479-Ab-1/ GM-Tg-hg-T95479-Ab-2; GM-Tg-rg-T95479-Ab-1/ GM-Tg-rg-T95479-Ab-2; GM-Tg-mg-T95479-Ab-1/ GM-Tg-mg-T95479-Ab-2; GM-Tg-cynog-T95479-Ab-1/ GM-Tg-cynog-T95479-Ab-2; GM-Tg-felg-T95479-Ab-1/ GM-Tg-felg-T95479-Ab-2; GM-Tg-cang-T95479-Ab-1/ GM-Tg-cang-T95479-Ab-2; GM-Tg-bovg-T95479-Ab-1/ GM-Tg-bovg-T95479-Ab-2; GM-Tg-equg-T95479-Ab-1/ GM-Tg-equg-T95479-Ab-2 |
| Products Name | Anti-SST monoclonal antibody |
| Format | mab |
| Target Name | SST |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SST benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T95479-Ag-1 | Recombinant multi-species SMS/ SST/ SMST protein |
| ORF Viral Vector | pGMLP000833 | human SST Lentivirus plasmid |
| ORF Viral Vector | vGMLP000833 | human SST Lentivirus particle |
| ORF Viral Vector | pGMLPm000283 | mouse Sst Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000283 | mouse Sst Lentivirus particle |
Target information
| Target ID | GM-T95479 |
| Target Name | SST |
| Gene ID | 6750,20604,24797,708626,403993,101096911,280932,100059610 |
| Gene Symbol and Synonyms | SMST,SOM,SRIF,SS,SS-14,SS-28,SST,SST1 |
| Uniprot Accession | P61278,P60042,P49670,P26917 |
| Uniprot Entry Name | SMS_HUMAN,SMS_RAT,SMS_CANLF,SMS_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | Esophagus Cancer, lung cancer |
| Gene Ensembl | ENSG00000157005 |
| Target Classification | N/A |
The target: SST, gene name: SST, also named as SMST. The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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