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Anti-PK3CG/ PIK3CG/ PI3CG monoclonal antibody
Anti-PK3CG/ PIK3CG/ PI3CG antibody for FACS & in-vivo assay
Go to PIK3CG/PIK3CG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T95913-Ab-1/ GM-Tg-hg-T95913-Ab-2 | Anti-Human PIK3CG monoclonal antibody | Human |
| GM-Tg-rg-T95913-Ab-1/ GM-Tg-rg-T95913-Ab-2 | Anti-Rat PIK3CG monoclonal antibody | Rat |
| GM-Tg-mg-T95913-Ab-1/ GM-Tg-mg-T95913-Ab-2 | Anti-Mouse PIK3CG monoclonal antibody | Mouse |
| GM-Tg-cynog-T95913-Ab-1/ GM-Tg-cynog-T95913-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIK3CG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T95913-Ab-1/ GM-Tg-felg-T95913-Ab-2 | Anti-Feline PIK3CG monoclonal antibody | Feline |
| GM-Tg-cang-T95913-Ab-1/ GM-Tg-cang-T95913-Ab-2 | Anti-Canine PIK3CG monoclonal antibody | Canine |
| GM-Tg-bovg-T95913-Ab-1/ GM-Tg-bovg-T95913-Ab-2 | Anti-Bovine PIK3CG monoclonal antibody | Bovine |
| GM-Tg-equg-T95913-Ab-1/ GM-Tg-equg-T95913-Ab-2 | Anti-Equine PIK3CG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T95913-Ab-1/ GM-Tg-hg-T95913-Ab-2; GM-Tg-rg-T95913-Ab-1/ GM-Tg-rg-T95913-Ab-2; GM-Tg-mg-T95913-Ab-1/ GM-Tg-mg-T95913-Ab-2; GM-Tg-cynog-T95913-Ab-1/ GM-Tg-cynog-T95913-Ab-2; GM-Tg-felg-T95913-Ab-1/ GM-Tg-felg-T95913-Ab-2; GM-Tg-cang-T95913-Ab-1/ GM-Tg-cang-T95913-Ab-2; GM-Tg-bovg-T95913-Ab-1/ GM-Tg-bovg-T95913-Ab-2; GM-Tg-equg-T95913-Ab-1/ GM-Tg-equg-T95913-Ab-2 |
| Products Name | Anti-PIK3CG monoclonal antibody |
| Format | mab |
| Target Name | PIK3CG |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PIK3CG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PK3CG/ PIK3CG/ PI3CG VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMAP000533 | Human PIK3CG Adenovirus particle |
| ORF Viral Vector | pGMAP000533 | Human PIK3CG Adenovirus plasmid |
| ORF Viral Vector | vGMAP000347 | Human PIK3CG Adenovirus particle |
| ORF Viral Vector | pGMAP000347 | Human PIK3CG Adenovirus plasmid |
Target information
| Target ID | GM-T95913 |
| Target Name | PIK3CG |
| Gene ID | 5294,30955,298947,698857,483266,101096215,530001,100050532 |
| Gene Symbol and Synonyms | 5830428L06Rik,IMD97,p110gamma,p120-PI3K,PI3CG,PI3K,PI3Kgamma,PIK3,PIK3CG |
| Uniprot Accession | P48736 |
| Uniprot Entry Name | PK3CG_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000105851 |
| Target Classification | Kinase |
The target: PIK3CG, gene name: PIK3CG, also named as PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K. Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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