Bovine GFAP antibody and antigen (recombinant protein)

Diagnostic anti-Bovine GFAP antibodies pairs and antigen for animal health (animal Bovines/Cattle Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-GFAP-Ag01Bovine GFAP$3090.00
GMP-BOV-GFAP-Ab01Anti-Bovine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-GFAP-Ab02Anti-Bovine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-GFAP-Ab03Anti-Bovine GFAP human monoclonal antibody (mAb)$3090.00
GMP-BOV-GFAP-Ab04Anti-Bovine GFAP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-GFAP-Ag01
Product NameBovine GFAP
Target/BiomarkerBovine GFAP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine GFAP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Bovines/Cattle with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsBovine GFAP
Product descriptionRecombinant Bovine GFAP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-GFAP-Ab01,GMP-BOV-GFAP-Ab02
Target/BiomarkerBovine GFAP
Product NameAnti-Bovine GFAP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine GFAP antibodies in Bovine GFAP level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine GFAP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine GFAP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-GFAP-Ab03,GMP-BOV-GFAP-Ab04
Target/BiomarkerBovine GFAP
Product NameAnti-Bovine GFAP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine GFAP antibodies in Bovine GFAP level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine GFAP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine GFAP, Glial Fibrillary Acidic Protein, occupies a central role in the intricate web of neuroglia within the central nervous system (CNS) of cattle. This protein is primarily expressed in astrocytes, a type of glial cell that serves as the backbone of neurological support and homeostasis. Structurally, GFAP belongs to the family of intermediate filaments, and its molecular design is optimized for providing structural stability to astrocytes.

    Astrocytes, often referred to as the "caretaker cells" of the CNS, play multifaceted roles in sustaining neuronal health and functionality. They are responsible for regulating neurotransmitter levels, providing metabolic support to neurons, and responding to CNS insults. Among their numerous functions, one of the most critical is their role as the first responders to neurological injury or stress.

    When the CNS of cattle faces adversity, such as injury, inflammation, or neurodegenerative conditions, astrocytes mount a dynamic response known as astrogliosis. This process involves the activation and proliferation of astrocytes and is accompanied by a marked increase in GFAP expression. The upregulation of GFAP serves a dual purpose: it reinforces the structural integrity of astrocytes and forms a barrier around damaged areas to prevent the spread of injury and inflammation.

    Therefore, measuring Bovine GFAP provides a direct window into the health of the CNS in cattle. Elevated levels of GFAP in cerebrospinal fluid (CSF) or bloodstream indicate an ongoing astrogliotic response, signaling the presence and extent of CNS damage or disease. The detection of increased GFAP levels is a pivotal step in the diagnostic process for neurological conditions, as it allows veterinarians to pinpoint the affected areas and gauge the severity of the neurological insult.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.