Bovine GFAP antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-BOV-GFAP-Ag01	Recombinant Bovine GFAP protein	3090
GMP-BOV-GFAP-Ab01	Anti-Bovine GFAP mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-BOV-GFAP-Ab02	Anti-Bovine GFAP mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-BOV-GFAP-Ab03	Anti-Bovine GFAP mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-BOV-GFAP-Ab04	Anti-Bovine GFAP mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-BOV-GFAP-Ag01
Product Name	Recombinant Bovine GFAP protein
Target/Biomarker	Bovine Glial fibrillary acid protein (GFAP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Glial fibrillary acid protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Bovine GFAP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-GFAP-Ab01, GMP-BOV-GFAP-Ab02, GMP-BOV-GFAP-Ab03, GMP-BOV-GFAP-Ab04
Product Name	Anti-Bovine GFAP mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Glial fibrillary acid protein (GFAP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Bovine Glial fibrillary acid protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Bovine GFAP mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Bovine GFAP, Glial Fibrillary Acidic Protein, occupies a central role in the intricate web of neuroglia within the central nervous system (CNS) of cattle. This protein is primarily expressed in astrocytes, a type of glial cell that serves as the backbone of neurological support and homeostasis. Structurally, GFAP belongs to the family of intermediate filaments, and its molecular design is optimized for providing structural stability to astrocytes. Astrocytes, often referred to as the "caretaker cells" of the CNS, play multifaceted roles in sustaining neuronal health and functionality. They are responsible for regulating neurotransmitter levels, providing metabolic support to neurons, and responding to CNS insults. Among their numerous functions, one of the most critical is their role as the first responders to neurological injury or stress. When the CNS of cattle faces adversity, such as injury, inflammation, or neurodegenerative conditions, astrocytes mount a dynamic response known as astrogliosis. This process involves the activation and proliferation of astrocytes and is accompanied by a marked increase in GFAP expression. The upregulation of GFAP serves a dual purpose: it reinforces the structural integrity of astrocytes and forms a barrier around damaged areas to prevent the spread of injury and inflammation. Therefore, measuring Bovine GFAP provides a direct window into the health of the CNS in cattle. Elevated levels of GFAP in cerebrospinal fluid (CSF) or bloodstream indicate an ongoing astrogliotic response, signaling the presence and extent of CNS damage or disease. The detection of increased GFAP levels is a pivotal step in the diagnostic process for neurological conditions, as it allows veterinarians to pinpoint the affected areas and gauge the severity of the neurological insult.

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