Bovine HABP antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Bovine HABP antibodies pairs and antigen for animal health (animal Bovines/Cattle rheumatoid arthritis (RA) andosteoarthritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Ruminants disease testing products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Bovine Hyaluronic Acid-Binding Protein (bHABP) stands as a pivotal biomarker in the intricate world of bovine physiology. Encoded by the bHABP gene, this glycoprotein is a member of the hyaluronic acid (HA)-binding protein family, boasting a crucial role in maintaining HA, a high molecular weight polysaccharide found abundantly in connective tissues, skin, and synovial fluid. HA's primary function is to uphold tissue hydration, lubrication, and shock absorption, and bHABP is its diligent guardian in the cattle's body.

HA, in its unadulterated form, is a critical component of various bovine tissues, contributing significantly to the structural integrity and resilience of connective tissues. However, HA is susceptible to enzymatic degradation and environmental factors, necessitating constant surveillance and protection. This is where bHABP emerges as a key player. It binds specifically to HA molecules, forming robust associations that shield HA from degradation, thus preserving tissue hydration and lubrication.

The importance of bHABP becomes most apparent in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating frictionless movement. When joints lack adequate HA levels and efficient HA-binding proteins like bHABP, they become vulnerable to wear and tear, leading to conditions like osteoarthritis—a painful and debilitating ailment in cattle.

Furthermore, bHABP's influence extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. This function is particularly critical for the structural integrity of the skin and mucous membranes. Additionally, bHABP has the capacity to interact with other proteins and participate in various signaling pathways, influencing processes such as tissue repair and inflammation.

About GDU