Bovine PG I antibody and antigen (recombinant protein)

Diagnostic anti-Bovine PG I antibodies pairs and antigen for animal health (animal Bovines/Cattle atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-PG-I-Ag01Bovine PG I$3090.00
GMP-BOV-PG-I-Ab01Anti-Bovine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-PG-I-Ab02Anti-Bovine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-PG-I-Ab03Anti-Bovine PG I human monoclonal antibody (mAb)$3090.00
GMP-BOV-PG-I-Ab04Anti-Bovine PG I human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-PG-I-Ag01
Product NameBovine PG I
Target/BiomarkerBovine PG I
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine PG I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Bovines/Cattle with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
TagHis
Reconized/Reactive SpecicsBovine PG I
Product descriptionRecombinant Bovine PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-PG-I-Ab01,GMP-BOV-PG-I-Ab02
Target/BiomarkerBovine PG I
Product NameAnti-Bovine PG I mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PG I antibodies in Bovine PG I level test of animal Bovines/Cattle with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Bovine PG I mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PG I antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-PG-I-Ab03,GMP-BOV-PG-I-Ab04
Target/BiomarkerBovine PG I
Product NameAnti-Bovine PG I human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PG I antibodies in Bovine PG I level test of animal Bovines/Cattle with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Bovine PG I mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine/Cattle Pepsinogen I (PG I) emerges as a captivating biomarker, offering profound insights into the complexities of bovine digestion. Structurally, PG I is an inactive zymogen, a precursor to the active enzyme pepsin, and it assumes a central role within the gastric mucosa of the cattle's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands.

    The journey of PG I commences with the ingestion of food. As dietary proteins enter the cattle's stomach, PG I stands poised for its transformation into pepsin. This metamorphosis unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG I to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall bovine health.

    Beyond its role as a digestive precursor, PG I serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG I is predominantly localized, is pivotal for its proper secretion. Disruptions in this mucosal lining, such as those observed in acidosis, gastric ulcers, or abomasal displacement, can alter PG I levels, offering valuable diagnostic insights.



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    GDU

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