Cow Pregnancy-associated glycoprotein 1 antibody and antigen (recombinant protein)

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Diagnostic anti-Cow Pregnancy-associated glycoprotein 1 antibodies pairs and antigen for animal health (animal Bovines/Cattle) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-Preg-ass-gly-1-Ag01	Cow Pregnancy-associated glycoprotein 1	$3090.00
GMP-BOV-Preg-ass-gly-1-Ab01	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	$3090.00
GMP-BOV-Preg-ass-gly-1-Ab02	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	$3090.00
GMP-BOV-Preg-ass-gly-1-Ab03	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	$3090.00
GMP-BOV-Preg-ass-gly-1-Ab04	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-BOV-Preg-ass-gly-1-Ag01
Product Name	Cow Pregnancy-associated glycoprotein 1
Target/Biomarker	not infectious
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Cow Pregnancy-associated glycoprotein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Cow Pregnancy-associated glycoprotein 1 level test of animal Bovines/Cattle.
Tag	His
Reconized/Reactive Specics	Cow Pregnancy-associated glycoprotein 1
Product description	Recombinant Cow Pregnancy-associated glycoprotein 1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-BOV-Preg-ass-gly-1-Ab01,GMP-BOV-Preg-ass-gly-1-Ab02
Target/Biomarker	not infectious
Product Name	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Cow Pregnancy-associated glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Cow Pregnancy-associated glycoprotein 1 antibodies in Cow Pregnancy-associated glycoprotein 1 level test of animal Bovines/Cattle.
Product description	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Cow Pregnancy-associated glycoprotein 1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-BOV-Preg-ass-gly-1-Ab03,GMP-BOV-Preg-ass-gly-1-Ab04
Target/Biomarker	not infectious
Product Name	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Cow Pregnancy-associated glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Cow Pregnancy-associated glycoprotein 1 antibodies in Cow Pregnancy-associated glycoprotein 1 level test of animal Bovines/Cattle.
Product description	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Pregnancy-Associated Glycoprotein 1 (PAG-1) stands as a distinctive biomarker that exemplifies the intricacies of bovine reproduction. Produced exclusively during gestation in cattle (Bos taurus), PAG-1 belongs to the family of pregnancy-associated glycoproteins, a group of proteins that exhibit selective expression during pregnancy, setting them apart from non-pregnant states.

The journey of PAG-1 commences with the successful implantation of the conceptus in the uterine wall. Placental cells, particularly binucleate trophoblast cells, undertake the synthesis and secretion of PAG-1. This specialized protein gradually finds its way into the maternal bloodstream, where its presence becomes detectable. Notably, PAG-1 is not just a single entity but represents a group of related proteins, each with distinct properties and roles within the context of bovine pregnancy.

While the precise biological functions of PAG-1 are subjects of ongoing scientific exploration, it is believed to partake in immunomodulation, a crucial process that ensures the maternal immune system tolerates the presence of the developing fetus. PAG-1 is thought to contribute to the establishment of immunological tolerance, preventing the mother's immune system from recognizing the fetus as a foreign entity. This immunomodulatory function is vital for the success of pregnancy and the protection of the developing embryo and fetus from immune-mediated harm.

Additionally, PAG-1 may play roles in placental development and nutrient transport. As pregnancy progresses, the placenta undergoes dynamic changes to support the growing fetus. PAG-1's involvement in these processes underscores its significance in the orchestration of bovine reproduction., The measurement of Pregnancy-Associated Glycoprotein 1 (PAG-1) is both a practical necessity and a scientific pursuit that converges to enhance cattle farming, reproductive management, and our understanding of bovine reproduction.

On the practical front, PAG-1 measurement serves as a linchpin in precise and timely pregnancy detection in cattle. Early confirmation of pregnancy is vital for effective herd management. By reliably identifying pregnant cows as early as 28 days post-conception, PAG-1 measurements empower farmers to tailor their herd management practices. This includes adjusting feeding regimes, preparing for calving, and optimizing resource allocation for pregnant animals. Early detection not only enhances herd health but also minimizes stress on pregnant cows, contributing to their well-being.

PAG-1 measurements extend beyond pregnancy confirmation to offer a window into the progress of gestation. PAG-1 levels exhibit a progressive rise during pregnancy, reflecting the stage and well-being of the developing fetus. This information aids in making informed decisions regarding calving preparation, resource allocation, and overall herd management. It allows for proactive measures to optimize herd fertility and ensure the best possible outcomes for both cattle and farmers.

Additionally, PAG-1 measurements play a pivotal role in identifying potential reproductive issues and complications. Variations in PAG-1 levels can serve as early indicators of problems such as embryonic loss or fetal abnormalities. Early detection of these issues facilitates timely veterinary interventions and management strategies to safeguard herd fertility and minimize economic losses, reinforcing the importance of PAG-1 as a tool for reproductive health assessment.

From a scientific perspective, PAG-1 research offers a gateway to unravel the intricate mechanisms of bovine reproduction and placental biology. Ongoing scientific investigations seek to elucidate the precise roles of PAG-1 in immunomodulation, placental development, and nutrient transport. These studies advance our understanding of bovine reproductive physiology and have broader implications for improving fertility management practices in cattle.

Furthermore, PAG-1 measurements play a pivotal role in the realm of assisted reproductive technologies (ART) used in cattle breeding. ART procedures, including embryo transfer and in vitro fertilization (IVF), rely on precise timing and successful implantation. Monitoring PAG-1 levels offers a reliable means to assess the success of these procedures, refine protocols, and make informed decisions regarding reproductive program optimization.

In summation, the measurement of Pregnancy-Associated Glycoprotein 1 (PAG-1) exemplifies the fusion of practical applications and scientific exploration in the domains of cattle farming, reproductive management, and bovine reproductive biology. Its pivotal role in early pregnancy detection, reproductive health assessment, and scientific research serves as a testament to the harmony between agricultural advancements and scientific progress, ultimately benefiting both the agricultural industry and our understanding of reproductive physiology.

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