Bovine Tau antibody and antigen (recombinant protein)

Diagnostic anti-Bovine Tau antibodies pairs and antigen for animal health (animal Bovines/Cattle Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-Tau-Ag01Bovine Tau$3090.00
GMP-BOV-Tau-Ab01Anti-Bovine Tau mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-Tau-Ab02Anti-Bovine Tau mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-Tau-Ab03Anti-Bovine Tau human monoclonal antibody (mAb)$3090.00
GMP-BOV-Tau-Ab04Anti-Bovine Tau human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-Tau-Ag01
Product NameBovine Tau
Target/BiomarkerBovine Tau
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine Tau antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Tau level test of animal Bovines/Cattle with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsBovine Tau
Product descriptionRecombinant Bovine Tau protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-Tau-Ab01,GMP-BOV-Tau-Ab02
Target/BiomarkerBovine Tau
Product NameAnti-Bovine Tau mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Tau antibodies in Bovine Tau level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine Tau mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Tau antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-Tau-Ab03,GMP-BOV-Tau-Ab04
Target/BiomarkerBovine Tau
Product NameAnti-Bovine Tau human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine Tau antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine Tau antibodies in Bovine Tau level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine Tau mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine Tau stands as a sentinel in the intricate landscape of cattle neurobiology. This protein, primarily localized within the central nervous system (CNS) of cattle, serves as a guardian of neuronal structural integrity and function. Its structural and functional homology to tau proteins in other species, including humans, underscores its critical role in maintaining proper neurological health.

    Structurally, Bovine Tau belongs to the tau protein family, sharing genetic and functional commonalities with its counterparts in diverse organisms. Its primary function is to bind to microtubules within neurons, promoting their assembly and stability. Microtubules are essential cellular structures that facilitate axonal transport, synaptic plasticity, and overall neuronal communication.

    However, the equilibrium of tau proteins like Bovine Tau can be disrupted in the context of neurodegenerative conditions observed in cattle. Tau proteins may undergo post-translational modifications, including hyperphosphorylation. These modifications lead to tau proteins adopting atypical conformations, rendering them susceptible to aggregation. The aggregation of tau proteins culminates in the formation of neurofibrillary tangles within neurons. These tangles impede axonal transport, compromise synaptic function, and eventually result in neuronal dysfunction and degeneration.

    The presence of elevated levels of Bovine Tau in specific contexts can serve as an indicator of these pathological processes, signaling the potential emergence of cognitive and neurological deficits in affected cattle.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.