Bovine VDBP antibody and antigen (recombinant protein)

Diagnostic anti-Bovine VDBP antibodies pairs and antigen for animal health (animal Bovines/Cattle liver failure, type I diabetes, cystic fibrosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-VDBP-Ag01Bovine VDBP$3090.00
GMP-BOV-VDBP-Ab01Anti-Bovine VDBP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-VDBP-Ab02Anti-Bovine VDBP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-VDBP-Ab03Anti-Bovine VDBP human monoclonal antibody (mAb)$3090.00
GMP-BOV-VDBP-Ab04Anti-Bovine VDBP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-VDBP-Ag01
Product NameBovine VDBP
Target/BiomarkerBovine VDBP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine VDBP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in VDBP level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
TagHis
Reconized/Reactive SpecicsBovine VDBP
Product descriptionRecombinant Bovine VDBP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-VDBP-Ab01,GMP-BOV-VDBP-Ab02
Target/BiomarkerBovine VDBP
Product NameAnti-Bovine VDBP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine VDBP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine VDBP antibodies in Bovine VDBP level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
Product descriptionAnti-Bovine VDBP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine VDBP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-VDBP-Ab03,GMP-BOV-VDBP-Ab04
Target/BiomarkerBovine VDBP
Product NameAnti-Bovine VDBP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine VDBP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine VDBP antibodies in Bovine VDBP level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
Product descriptionAnti-Bovine VDBP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Vitamin D-Binding Protein (VDBP) in cattle, or bovines, emerges as a multifunctional sentinel, standing at the crossroads of vitamin D metabolism and immune modulation within these robust animals. Structurally, VDBP is a glycoprotein, with a molecular weight of approximately 58-59 kDa, synthesized predominantly in the liver before embarking on its journey through the bloodstream.

    At the heart of VDBP's mission lies the transportation of vitamin D metabolites, with a primary emphasis on vitamin D3. Functioning as a carrier protein, VDBP binds to vitamin D and embarks on a journey that ensures its safe and efficient delivery to target tissues and cells throughout the bovine body. This meticulous oversight is crucial, as vitamin D is a linchpin in the regulation of calcium and phosphorus homeostasis, profoundly impacting bone health, muscle function, and an array of physiological processes fundamental to cattle well-being.

    The journey of vitamin D, under VDBP's vigilant guidance, involves a choreography of interactions with various tissues. It influences the intestinal absorption of calcium and phosphorus, vital for skeletal integrity and muscle contraction. Additionally, vitamin D plays a role in immune responses, cell proliferation, and differentiation, underscoring its significance as a regulator of both musculoskeletal and immune functions in cattle.

    However, VDBP's role transcends vitamin D transport; it extends into the domain of immunomodulation. VDBP exerts its influence on the immune system by interacting with immune cells, particularly macrophages. This interaction modulates immune responses, highlighting VDBP's role as a pivotal component of the bovine immune system. It acts as a bridge between vitamin D metabolism and immune functions, underscoring its multifaceted nature within the intricate framework of cattle physiology.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.