Bovine cTnI antibody and antigen (recombinant protein)

Diagnostic anti-Bovine cTnI antibodies pairs and antigen for animal health (animal Bovines/Cattle myocardial infarction) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-cTnI-Ag01Bovine cTnI$3090.00
GMP-BOV-cTnI-Ab01Anti-Bovine cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-cTnI-Ab02Anti-Bovine cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-cTnI-Ab03Anti-Bovine cTnI human monoclonal antibody (mAb)$3090.00
GMP-BOV-cTnI-Ab04Anti-Bovine cTnI human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-cTnI-Ag01
Product NameBovine cTnI
Target/BiomarkerBovine cTnI
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine cTnI antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnI level test of animal Bovines/Cattle with myocardial infarction.
TagHis
Reconized/Reactive SpecicsBovine cTnI
Product descriptionRecombinant Bovine cTnI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-cTnI-Ab01,GMP-BOV-cTnI-Ab02
Target/BiomarkerBovine cTnI
Product NameAnti-Bovine cTnI mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine cTnI antibodies in Bovine cTnI level test of animal Bovines/Cattle with myocardial infarction.
Product descriptionAnti-Bovine cTnI mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine cTnI antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-cTnI-Ab03,GMP-BOV-cTnI-Ab04
Target/BiomarkerBovine cTnI
Product NameAnti-Bovine cTnI human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine cTnI antibodies in Bovine cTnI level test of animal Bovines/Cattle with myocardial infarction.
Product descriptionAnti-Bovine cTnI mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cardiac Troponin I (cTnI), a cardiac-specific biomarker, holds a position of utmost importance in bovine (cattle) physiology, particularly in the realm of cardiac health assessment. This protein, predominantly found in the bloodstream of cattle, serves as a critical indicator of cardiac well-being. To grasp the full significance of cTnI, it is imperative to delve into its structural attributes, functional role, and its profound implications in bovine cardiology.

    Structurally, cTnI is one of the three subunits of the troponin complex, the others being cardiac Troponin T (cTnT) and cardiac Troponin C (cTnC). This complex is strategically located within the sarcomeres of cardiac muscle fibers, where it exerts meticulous control over muscle contraction. The precision of this regulation is pivotal for the efficient pumping of blood by the bovine heart.

    What sets cTnI apart is its remarkable cardiac specificity. While other troponin isoforms exist in skeletal muscle, cTnI is exclusively expressed in the heart. This exclusivity makes cTnI an extraordinarily specific biomarker for assessing cardiac muscle injury or damage. When cardiac cells are compromised due to factors such as myocardial infarction, cardiac diseases, or cardiac trauma, cTnI is released into the bloodstream. Consequently, elevated levels of cTnI in a bovine's blood can serve as a critical diagnostic indicator of cardiac health.

    The detection of cTnI in cattle is typically accomplished through immunoassays, such as enzyme-linked immunosorbent assays (ELISA). These assays provide a quantitative measure of cTnI concentration, enabling veterinarians to evaluate the extent of cardiac injury or disease. The sensitivity of these assays is such that even minor myocardial damage can lead to detectable elevations in cTnI levels, enabling early diagnosis and intervention.



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    GDU

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