Canine C-Peptide antibody and antigen (recombinant protein)

Diagnostic anti-Canine C-Peptide antibodies pairs and antigen for animal health (animal Dog/Canine type 1 diabetes mellitus) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-C-Peptide-Ag01Canine C-Peptide$3090.00
GMP-CAN-C-Peptide-Ab01Anti-Canine C-Peptide mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-C-Peptide-Ab02Anti-Canine C-Peptide mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-C-Peptide-Ab03Anti-Canine C-Peptide human monoclonal antibody (mAb)$3090.00
GMP-CAN-C-Peptide-Ab04Anti-Canine C-Peptide human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-C-Peptide-Ag01
Product NameCanine C-Peptide
Target/BiomarkerCanine C-Peptide
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine C-Peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
TagHis
Reconized/Reactive SpecicsCanine C-Peptide
Product descriptionRecombinant Canine C-Peptide protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-C-Peptide-Ab01,GMP-CAN-C-Peptide-Ab02
Target/BiomarkerCanine C-Peptide
Product NameAnti-Canine C-Peptide mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine C-Peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine C-Peptide antibodies in Canine C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
Product descriptionAnti-Canine C-Peptide mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine C-Peptide antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-C-Peptide-Ab03,GMP-CAN-C-Peptide-Ab04
Target/BiomarkerCanine C-Peptide
Product NameAnti-Canine C-Peptide human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine C-Peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine C-Peptide antibodies in Canine C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
Product descriptionAnti-Canine C-Peptide mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine C-Peptide, a molecular marvel of 31 amino acids, is intricately woven into the fabric of dogs' metabolic harmony. This peptide is the result of the proteolytic cleavage of proinsulin during its conversion into active insulin. While insulin takes center stage in glucose regulation, C-Peptide quietly plays its role as a companion biomarker, co-secreted alongside insulin by the pancreas.

    Canine C-Peptide emerges as a sentinel of pancreatic health and insulin production. It mirrors the natural ebb and flow of endogenous insulin secretion, pulsing into circulation in response to rising blood glucose levels. Unlike exogenously administered insulin, which is uniform and continuous, C-Peptide levels follow a distinct pattern that mimics the body's physiological insulin release. This pattern offers a unique window into the functioning of the pancreas, enabling veterinarians to assess the organ's ability to produce insulin.

    Furthermore, Canine C-Peptide serves as a linchpin in the diagnosis and differentiation of diabetes in dogs. It distinguishes between Type 1 and Type 2 diabetes, two distinct entities in the spectrum of canine diabetes. In Type 1 diabetes, C-Peptide levels are typically low or undetectable, signifying the autoimmune destruction of pancreatic beta cells and the absence of endogenous insulin production. In Type 2 diabetes, C-Peptide levels vary, reflecting the interplay of insulin resistance and impaired insulin secretion. This differentiation is pivotal, as it dictates treatment strategies and guides veterinarians in providing tailored care for dogs.



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