Canine cystatin C antibody and antigen (recombinant protein)

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Diagnostic anti-Canine cystatin C antibodies pairs and antigen for animal health (animal Dog/Canine Hormone disorders) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CysC-Ag01	cystatin C (CysC)	$3090.00
GMP-CAN-CysC-Ab01	Anti-Canine cystatin C mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-CysC-Ab02	Anti-Canine cystatin C mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-CysC-Ab03	Anti-Canine cystatin C human monoclonal antibody (mAb)	$3090.00
GMP-CAN-CysC-Ab04	Anti-Canine cystatin C human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-CAN-CysC-Ag01
Product Name	cystatin C (CysC)
Target/Biomarker	cystatin C (CysC)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine cystatin C antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cystatin C (CysC) level test of animal Dog/Canine with Hormone disorders.
Tag	His
Reconized/Reactive Specics	cystatin C (CysC)
Product description	Recombinant Canine cystatin C protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-CysC-Ab01,GMP-CAN-CysC-Ab02
Target/Biomarker	cystatin C (CysC)
Product Name	Anti-Canine cystatin C mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies in cystatin C (CysC) level test of animal Dog/Canine with Hormone disorders.
Product description	Anti-Canine cystatin C mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-CysC-Ab03,GMP-CAN-CysC-Ab04
Target/Biomarker	cystatin C (CysC)
Product Name	Anti-Canine cystatin C human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Canine cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cystatin C (CysC) antibodies in cystatin C (CysC) level test of animal Dog/Canine with Hormone disorders.
Product description	Anti-Canine cystatin C mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Canine CYSC, or Cystatin C, may be unassuming in size, but its significance in the landscape of canine health cannot be overstated. This unpretentious protein operates as a sentinel, a vigilant monitor of the intricate machinery within a dog's body, specifically, the renal system.

Produced by nucleated cells throughout a dog's body at a constant rate, Canine CYSC finds its moment in the spotlight within the kidneys, where it plays a pivotal role in assessing renal health. Its journey begins with the glomeruli, the kidney's intricate filtration units. Here, Canine CYSC is freely filtered from the blood, representing the initial step in evaluating kidney function.

After its passage through the glomeruli, Canine CYSC embarks on a voyage through the renal tubules, where it faces a fate determined by the kidneys' filtration efficiency. In healthy dogs, the majority of CYSC is reabsorbed and subsequently catabolized by the tubules. This process ensures that Canine CYSC levels in the bloodstream remain relatively stable, mirroring the efficiency of glomerular filtration.

The beauty of Canine CYSC lies in its sensitivity and specificity as a biomarker for renal health. Unlike traditional markers such as creatinine, Canine CYSC is less influenced by factors like muscle mass or diet. Consequently, it offers a more accurate reflection of glomerular filtration rate (GFR), making it an indispensable tool for assessing kidney function in dogs.

Canine CYSC's ability to detect subtle changes in renal function, especially in the early stages of kidney disease, makes it a crucial asset for veterinarians. Its role extends far beyond diagnosis; it is a herald of proactive healthcare. By measuring CYSC levels, veterinarians can identify renal issues in their nascent stages, enabling timely intervention and a higher likelihood of successful treatment.

The imperative to measure Canine CYSC reaches beyond the realm of laboratory analyses; it embarks on a journey of profound scientific and clinical significance. This journey promises to redefine our approach to renal health in dogs and enhance our capacity to safeguard their well-being.

Canine CYSC's significance hinges on its ability to gauge glomerular filtration rate (GFR), a fundamental pillar of renal function. GFR represents the kidneys' efficiency in filtering waste products, maintaining fluid balance, and eliminating metabolic byproducts. In dogs, where precise metabolic regulation is essential for overall health, GFR is a lifeline.

What sets Canine CYSC apart as a biomarker is its sensitivity and specificity, particularly in the context of renal health. Unlike traditional markers like creatinine, Canine CYSC is less susceptible to external influences. Muscle mass or diet variations, which can confound other markers, have minimal impact on CYSC levels. This makes CYSC a reliable yardstick for evaluating renal function, especially in its earliest stages.

The clinical implications of Canine CYSC measurement are multifaceted. Firstly, it serves as an invaluable diagnostic tool. Elevated CYSC levels can raise the alarm, prompting veterinarians to investigate the root cause of kidney dysfunction. Early detection can be a game-changer, allowing for timely intervention, the initiation of treatment, and a more favorable prognosis for canine patients.

Beyond diagnosis, Canine CYSC serves as a compass for disease monitoring and therapeutic interventions. By regularly assessing CYSC levels in dogs with renal disease, veterinarians gain a dynamic view of disease progression. This enables them to tailor treatment strategies, fine-tuning medications, dietary plans, and fluid management to the unique needs of each patient. The result is not just an extension of lifespan but an improvement in the quality of life for canine companions.

Canine CYSC also fuels the engine of scientific research. It offers a deeper understanding of renal function and dysfunction in dogs, paving the way for innovative treatments and interventions. Researchers can explore the nuances of kidney disease, unraveling its molecular underpinnings and developing novel therapies guided by insights gleaned from CYSC measurements.

Moreover, in an era where preventive healthcare takes center stage, Canine CYSC emerges as a harbinger of proactive well-being. Regular monitoring of CYSC levels in apparently healthy dogs can flag subtle shifts in renal function, allowing for preemptive measures to maintain kidney health and prevent the onset of disease.

In conclusion, the measurement of Canine CYSC transcends the laboratory setting; it represents a pledge to safeguard the well-being of our canine companions. It illuminates the path to healthier dogs, more effective treatments, and a deeper appreciation for the role of biomarkers in modern veterinary medicine.

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