Canine HABP antibody and antigen (recombinant protein)

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Diagnostic anti-Canine HABP antibodies pairs and antigen for animal health (animal Dog/Canine rheumatoid arthritis (RA) andosteoarthritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

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Target/Biomarker Information

Canine Hyaluronic Acid-Binding Protein (cHABP) emerges as a fundamental player in the intricate world of canine physiology. This glycoprotein, encoded by the cHABP gene, specializes in the orchestration of hyaluronic acid (HA), a prominent constituent of the extracellular matrix. HA's primary role is to maintain tissue hydration, lubrication, and resilience, and cHABP is its faithful guardian in the canine body.

HA, a high molecular weight polysaccharide, resides in various tissues in dogs, including connective tissues, skin, and synovial fluid. Its biophysical properties make it a vital component for proper joint function and overall tissue health. However, HA is prone to degradation and requires constant vigilance to maintain its integrity. This is where cHABP steps in. cHABP forms tight bonds with HA molecules, effectively shielding them from enzymatic degradation and environmental factors.

The significance of cHABP becomes particularly evident in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating smooth articulation and reducing friction during movement. Without adequate HA levels and efficient HA-binding proteins like cHABP, joints may become susceptible to wear and tear, leading to conditions like osteoarthritis, a painful and debilitating ailment in dogs.

Moreover, cHABP's role extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. In doing so, it supports overall tissue integrity, wound healing, and the body's ability to withstand mechanical stress. Furthermore, cHABP interacts with other proteins and participates in various signaling pathways, influencing processes like tissue repair and inflammation.

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