Canine HBP antibody and antigen (recombinant protein)

Diagnostic anti-Canine HBP antibodies pairs and antigen for animal health (animal Dog/Canine inflammation/autoimmune/ inflammatory disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-HBP-Ag01Canine HBP$3090.00
GMP-CAN-HBP-Ab01Anti-Canine HBP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-HBP-Ab02Anti-Canine HBP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-HBP-Ab03Anti-Canine HBP human monoclonal antibody (mAb)$3090.00
GMP-CAN-HBP-Ab04Anti-Canine HBP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-HBP-Ag01
Product NameCanine HBP
Target/BiomarkerCanine HBP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine HBP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HBP level test of animal Dog/Canine with inflammation/autoimmune/ inflammatory disease.
TagHis
Reconized/Reactive SpecicsCanine HBP
Product descriptionRecombinant Canine HBP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-HBP-Ab01,GMP-CAN-HBP-Ab02
Target/BiomarkerCanine HBP
Product NameAnti-Canine HBP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine HBP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HBP antibodies in Canine HBP level test of animal Dog/Canine with inflammation/autoimmune/ inflammatory disease.
Product descriptionAnti-Canine HBP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HBP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-HBP-Ab03,GMP-CAN-HBP-Ab04
Target/BiomarkerCanine HBP
Product NameAnti-Canine HBP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine HBP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine HBP antibodies in Canine HBP level test of animal Dog/Canine with inflammation/autoimmune/ inflammatory disease.
Product descriptionAnti-Canine HBP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Heparin-binding protein (HBP) in dogs represents a remarkable example of the immune system's adaptability and multifaceted capabilities. Synthesized and secreted primarily by neutrophils, HBP plays a pivotal role in orchestrating immune responses and contributing to the body's defense mechanisms.

    Structurally, HBP exhibits a unique affinity for heparin, a glycosaminoglycan present in the extracellular matrix of tissues. This binding property allows HBP to interact with a range of molecules, facilitating its involvement in various immune processes.

    One of HBP's primary functions in dogs is its role as a potent chemotactic agent. It acts as a signal, guiding immune cells, particularly neutrophils, to sites of infection or tissue damage. This chemotactic activity is crucial for the rapid and effective mobilization of immune defenses, enabling the containment and elimination of pathogens.

    Beyond its chemotactic role, HBP possesses antimicrobial properties. It targets bacterial membranes, disrupting their integrity and promoting bacterial cell lysis. This antimicrobial activity contributes to the innate immune response and complements the efforts of other immune components in fighting infections.

    Additionally, HBP plays a vital role in angiogenesis, the process of forming new blood vessels. This function is integral to tissue repair and regeneration. By modulating angiogenesis, HBP supports the delivery of oxygen and nutrients to injured tissues, facilitating their healing and recovery.



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