Canine Ins antibody and antigen (recombinant protein)

Diagnostic anti-Canine Ins antibodies pairs and antigen for animal health (animal Dog/Canine Diabetes mellitus) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-Ins-Ag01Canine Ins$3090.00
GMP-CAN-Ins-Ab01Anti-Canine Ins mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-Ins-Ab02Anti-Canine Ins mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-Ins-Ab03Anti-Canine Ins human monoclonal antibody (mAb)$3090.00
GMP-CAN-Ins-Ab04Anti-Canine Ins human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-Ins-Ag01
Product NameCanine Ins
Target/BiomarkerCanine Ins
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine Ins antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Ins level test of animal Dog/Canine with Diabetes mellitus.
TagHis
Reconized/Reactive SpecicsCanine Ins
Product descriptionRecombinant Canine Ins protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-Ins-Ab01,GMP-CAN-Ins-Ab02
Target/BiomarkerCanine Ins
Product NameAnti-Canine Ins mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine Ins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Ins antibodies in Canine Ins level test of animal Dog/Canine with Diabetes mellitus.
Product descriptionAnti-Canine Ins mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Ins antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-Ins-Ab03,GMP-CAN-Ins-Ab04
Target/BiomarkerCanine Ins
Product NameAnti-Canine Ins human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine Ins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine Ins antibodies in Canine Ins level test of animal Dog/Canine with Diabetes mellitus.
Product descriptionAnti-Canine Ins mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Insulin, when associated with Human Insulin, embodies the essence of a finely tuned molecular machinery that regulates glucose metabolism in dogs. It is produced by the beta cells of the canine pancreas and plays a pivotal role in the intricate web of metabolic processes that maintain blood sugar equilibrium.

    While there are subtle structural differences between Canine Insulin and its human counterpart, they share fundamental similarities in their mechanisms of action. Both insulins serve as molecular keys, unlocking the doors of cells to allow glucose uptake from the bloodstream. This glucose uptake is essential for energy production, fueling the various cellular processes that sustain life.

    In the context of diabetic dogs, Canine Insulin often refers to Human Insulin, which is used therapeutically to restore glycemic control. Diabetes mellitus in dogs can manifest as Type 1 or Type 2 diabetes. In Type 1 diabetes, the pancreas fails to produce sufficient insulin, while in Type 2 diabetes, the cells exhibit reduced responsiveness to insulin. In either case, elevated blood glucose levels are the hallmark.

    The administration of Human Insulin in diabetic dogs addresses this underlying deficiency or resistance, enabling glucose uptake by cells and thus lowering blood sugar levels. While Human Insulin isn't identical to Canine Insulin, its efficacy in managing canine diabetes is well-established, making it a mainstay in veterinary medicine.



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    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.