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Canine MPO antibody and antigen (recombinant protein)
Diagnostic anti-Canine MPO antibodies pairs and antigen for animal health (animal Dog/Canine vascular inflammation) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-MPO-Ag01 | Canine MPO | $3090.00 |
| GMP-CAN-MPO-Ab01 | Anti-Canine MPO mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-MPO-Ab02 | Anti-Canine MPO mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-MPO-Ab03 | Anti-Canine MPO human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-MPO-Ab04 | Anti-Canine MPO human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-MPO-Ag01 |
| Product Name | Canine MPO |
| Target/Biomarker | Canine MPO |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine MPO antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MPO level test of animal Dog/Canine with vascular inflammation. |
| Tag | His | Reconized/Reactive Specics | Canine MPO |
| Product description | Recombinant Canine MPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-MPO-Ab01,GMP-CAN-MPO-Ab02 |
| Target/Biomarker | Canine MPO |
| Product Name | Anti-Canine MPO mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine MPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine MPO antibodies in Canine MPO level test of animal Dog/Canine with vascular inflammation. |
| Product description | Anti-Canine MPO mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine MPO antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-MPO-Ab03,GMP-CAN-MPO-Ab04 |
| Target/Biomarker | Canine MPO |
| Product Name | Anti-Canine MPO human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine MPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine MPO antibodies in Canine MPO level test of animal Dog/Canine with vascular inflammation. |
| Product description | Anti-Canine MPO mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Myeloperoxidase (MPO) is an enzyme of paramount importance within the canine immune system, specifically within neutrophils, the body's first line of defense against invading pathogens. MPO is housed primarily in the azurophilic granules of these specialized white blood cells. It serves as a critical component of the canine innate immune response.
Structurally, MPO is a heme-containing enzyme, which means it contains iron atoms at its core. When neutrophils encounter microbial invaders, they unleash MPO into the surrounding environment as part of their antimicrobial weaponry. MPO's primary function is to catalyze the production of hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride ions (Cl-). HOCl is a potent and reactive antimicrobial agent capable of swiftly neutralizing a broad spectrum of microorganisms, including bacteria, fungi, and viruses.
MPO's mechanism of action involves the generation of reactive oxygen species (ROS), such as superoxide radicals and hydrogen peroxide, which are toxic to pathogens. Additionally, MPO promotes the conversion of chloride ions into hypochlorous acid, which exhibits potent antimicrobial properties, further enhancing the neutrophils' ability to eliminate invaders.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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