Canine NGAL antibody and antigen (recombinant protein)

Diagnostic anti-Canine NGAL antibodies pairs and antigen for animal health (animal Dog/Canine kidney injury) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-NGAL-Ag01Canine NGAL$3090.00
GMP-CAN-NGAL-Ab01Anti-Canine NGAL mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-NGAL-Ab02Anti-Canine NGAL mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-NGAL-Ab03Anti-Canine NGAL human monoclonal antibody (mAb)$3090.00
GMP-CAN-NGAL-Ab04Anti-Canine NGAL human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-NGAL-Ag01
Product NameCanine NGAL
Target/BiomarkerCanine NGAL
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine NGAL antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NGAL level test of animal Dog/Canine with kidney injury.
TagHis
Reconized/Reactive SpecicsCanine NGAL
Product descriptionRecombinant Canine NGAL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-NGAL-Ab01,GMP-CAN-NGAL-Ab02
Target/BiomarkerCanine NGAL
Product NameAnti-Canine NGAL mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine NGAL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NGAL antibodies in Canine NGAL level test of animal Dog/Canine with kidney injury.
Product descriptionAnti-Canine NGAL mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NGAL antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-NGAL-Ab03,GMP-CAN-NGAL-Ab04
Target/BiomarkerCanine NGAL
Product NameAnti-Canine NGAL human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine NGAL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NGAL antibodies in Canine NGAL level test of animal Dog/Canine with kidney injury.
Product descriptionAnti-Canine NGAL mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine NGAL, or Neutrophil Gelatinase-Associated Lipocalin, is a relatively small but mighty glycoprotein with far-reaching significance in the realm of canine health. It operates as a sentinel, a vigilant guardian of the intricate renal machinery within a dog's body, specifically, the renal tubules.

    Synthesized and released by various cells, including neutrophils and renal tubular cells, Canine NGAL is poised to respond to renal distress with remarkable speed. When acute kidney injury (AKI) strikes, whether due to toxins, infections, or other factors, Canine NGAL swiftly enters the bloodstream. This rapid release positions NGAL as one of the earliest indicators of renal dysfunction in dogs, often preceding other traditional markers.

    Canine NGAL's journey through the renal tubules holds critical insights into its role as a biomarker. In healthy dogs, the majority of NGAL is reabsorbed by the renal tubules and catabolized. However, in the presence of renal injury or stress, this finely tuned process is disrupted. As a result, NGAL levels rise, serving as a beacon of distress and an early warning system for veterinarians.

    The true strength of Canine NGAL is its sensitivity and specificity. It detects renal injury at its inception, often before clinical symptoms manifest. This early detection is a game-changer in the management of AKI, allowing for prompt intervention and treatment. Timely action can significantly improve the prognosis for canine patients, preserving both their quality of life and longevity.



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