Canine PIIINP antibody and antigen (recombinant protein)

Diagnostic anti-Canine PIIINP antibodies pairs and antigen for animal health (animal Dog/Canine liver fibrosis and cirrhosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-PIIINP-Ag01Canine PIIINP$3090.00
GMP-CAN-PIIINP-Ab01Anti-Canine PIIINP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PIIINP-Ab02Anti-Canine PIIINP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PIIINP-Ab03Anti-Canine PIIINP human monoclonal antibody (mAb)$3090.00
GMP-CAN-PIIINP-Ab04Anti-Canine PIIINP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-PIIINP-Ag01
Product NameCanine PIIINP
Target/BiomarkerCanine PIIINP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine PIIINP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
TagHis
Reconized/Reactive SpecicsCanine PIIINP
Product descriptionRecombinant Canine PIIINP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PIIINP-Ab01,GMP-CAN-PIIINP-Ab02
Target/BiomarkerCanine PIIINP
Product NameAnti-Canine PIIINP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine PIIINP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PIIINP antibodies in Canine PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
Product descriptionAnti-Canine PIIINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PIIINP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PIIINP-Ab03,GMP-CAN-PIIINP-Ab04
Target/BiomarkerCanine PIIINP
Product NameAnti-Canine PIIINP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine PIIINP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PIIINP antibodies in Canine PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
Product descriptionAnti-Canine PIIINP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Procollagen Type III N-Terminal Propeptide (PIIINP) emerges as a linchpin in the intricate world of connective tissues within dogs. Functionally, PIIINP serves as a sentinel, a molecular messenger that reveals the ongoing story of collagen synthesis and connective tissue remodeling.

    Structurally, PIIINP is derived from the precursor molecule procollagen Type III. During collagen production, procollagen undergoes enzymatic processing, resulting in the formation of collagen fibers. PIIINP represents the N-terminal propeptide of this collagen subtype, a marker for the inception of collagen synthesis.

    Collagen, the primary structural protein in connective tissues, underpins the strength, flexibility, and resilience of tissues such as skin, tendons, and blood vessels. The continuous synthesis and degradation of collagen are pivotal processes, ensuring the dynamic adaptation and repair of these tissues. PIIINP, by virtue of its presence in collagen synthesis, offers a glimpse into this remarkable process.

    When connective tissues undergo remodeling or repair, PIIINP levels often fluctuate in response to changing demands. For instance, during wound healing, PIIINP production surges as the body mobilizes collagen to mend damaged tissue. Conversely, in pathological conditions like fibrosis, characterized by excessive collagen deposition, PIIINP levels can be persistently elevated, reflecting the ongoing fibrotic process.



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