Canine PINP antibody and antigen (recombinant protein)

Diagnostic anti-Canine PINP antibodies pairs and antigen for animal health (animal Dog/Canine osteoporosis therapy) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-PINP-Ag01Canine PINP$3090.00
GMP-CAN-PINP-Ab01Anti-Canine PINP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PINP-Ab02Anti-Canine PINP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PINP-Ab03Anti-Canine PINP human monoclonal antibody (mAb)$3090.00
GMP-CAN-PINP-Ab04Anti-Canine PINP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-PINP-Ag01
Product NameCanine PINP
Target/BiomarkerCanine PINP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine PINP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of animal Dog/Canine with osteoporosis therapy.
TagHis
Reconized/Reactive SpecicsCanine PINP
Product descriptionRecombinant Canine PINP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PINP-Ab01,GMP-CAN-PINP-Ab02
Target/BiomarkerCanine PINP
Product NameAnti-Canine PINP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine PINP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PINP antibodies in Canine PINP level test of animal Dog/Canine with osteoporosis therapy.
Product descriptionAnti-Canine PINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PINP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PINP-Ab03,GMP-CAN-PINP-Ab04
Target/BiomarkerCanine PINP
Product NameAnti-Canine PINP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine PINP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PINP antibodies in Canine PINP level test of animal Dog/Canine with osteoporosis therapy.
Product descriptionAnti-Canine PINP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Procollagen Type I N-Terminal Propeptide (Canine PINP) serves as a biological window into the intricate world of canine bone health. Comprising 244 amino acids, this biomarker is a fragment of procollagen, the precursor to collagen—the structural protein that forms the foundation of bones, tendons, ligaments, and various connective tissues in dogs.

    Within the physiological ballet of collagen production, Canine PINP emerges as a significant player. During the formation of collagen, procollagen molecules undergo a meticulous transformation, including enzymatic cleavage. Canine PINP is released as a byproduct of this process and enters the bloodstream. It becomes a messenger, conveying information about bone turnover, collagen synthesis, and the dynamic balance that maintains skeletal integrity.

    Canine PINP is essential for understanding the dynamics of bone remodeling in dogs. Bones are not static structures but are in a constant state of renewal and adaptation. Elevated levels of Canine PINP may signify heightened bone turnover, suggesting a state of rapid bone resorption and formation. In young dogs, this can be indicative of healthy growth, while in older dogs, it might raise concerns about osteoporosis or underlying metabolic conditions.

    Conversely, decreased Canine PINP levels may point to reduced collagen synthesis and impaired bone health. Conditions like osteoarthritis may be associated with such alterations in Canine PINP levels, reflecting the gradual wear and tear on joint cartilage and bone tissue.

    The measurement of Canine PINP involves a simple blood test, making it a practical tool in veterinary medicine. Veterinarians rely on Canine PINP assessments to diagnose bone-related disorders and evaluate the efficacy of interventions. For example, in cases of osteoporosis, elevated Canine PINP levels may trigger therapeutic measures to support bone health. These measures may include dietary modifications to ensure an adequate intake of calcium and vitamin D or medication to enhance bone density.



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