Canine Prog antigen antibody and antigen (recombinant protein)

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Diagnostic anti-Canine Prog antigen antibodies pairs and antigen for animal health (animal Dog/Canine Hormone disorders) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Prog-Ag01	Progesterone (Prog)	$3090.00
GMP-CAN-Prog-Ab01	Anti-Canine Prog antigen mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-Prog-Ab02	Anti-Canine Prog antigen mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-Prog-Ab03	Anti-Canine Prog antigen human monoclonal antibody (mAb)	$3090.00
GMP-CAN-Prog-Ab04	Anti-Canine Prog antigen human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-CAN-Prog-Ag01
Product Name	Progesterone (Prog)
Target/Biomarker	Progesterone (Prog)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Prog antigen antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Progesterone (Prog) level test of animal Dog/Canine with Hormone disorders.
Tag	His
Reconized/Reactive Specics	Progesterone (Prog)
Product description	Recombinant Canine Prog antigen protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-Prog-Ab01,GMP-CAN-Prog-Ab02
Target/Biomarker	Progesterone (Prog)
Product Name	Anti-Canine Prog antigen mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Prog antigen antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Progesterone (Prog) antibodies in Progesterone (Prog) level test of animal Dog/Canine with Hormone disorders.
Product description	Anti-Canine Prog antigen mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Progesterone (Prog) antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-Prog-Ab03,GMP-CAN-Prog-Ab04
Target/Biomarker	Progesterone (Prog)
Product Name	Anti-Canine Prog antigen human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Canine Prog antigen antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Progesterone (Prog) antibodies in Progesterone (Prog) level test of animal Dog/Canine with Hormone disorders.
Product description	Anti-Canine Prog antigen mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Progesterone (P4), a quintessential steroid hormone, stands as a linchpin in the intricate tapestry of female reproductive physiology across mammalian species, including dogs. Its synthesis primarily takes place in the corpus luteum, a transient endocrine structure that emerges within the ovary post-ovulation. Structurally, progesterone boasts a complex tetracyclic ring, placing it in the class of progestogens.

Progesterone's pivotal role in the reproductive cycle unfolds with remarkable precision. Its influence spans from orchestrating the menstrual cycle to preparing and maintaining the uterine environment during pregnancy. In non-pregnant females, progesterone levels remain low. However, upon conception, a transformative surge in progesterone levels occurs, signaling the initiation of a profound physiological shift.

One of progesterone's foremost functions is to prime the uterine environment for embryo implantation. It accomplishes this by stimulating the secretion of cervical mucus and glycogen within the uterine lining. This transformed milieu becomes a hospitable and nourishing sanctuary for the developing embryo. Moreover, progesterone promotes the development of uterine blood vessels, ensuring an ample supply of nutrients and oxygen through the placenta to the growing fetus.

During pregnancy, progesterone's role persists as a guardian of gestation. It wields its influence by inhibiting uterine contractions, thus safeguarding against premature labor. Furthermore, progesterone continues to nurture the placenta's growth and development, ensuring its optimal functioning throughout gestation., The measurement of progesterone levels in female dogs transcends the boundaries of reproductive convenience; it emerges as a multifaceted tool that serves as a compass for reproductive readiness, a sentinel for health monitoring, and a diagnostic beacon for a spectrum of reproductive conditions.

For breeders and veterinarians, progesterone testing is a pivotal asset in the realm of canine reproduction. It provides a precise gauge of a female dog's readiness for breeding or artificial insemination. As progesterone levels begin their ascent, marking the onset of ovulation, this critical data informs the ideal time for mating, ensuring the highest probability of a successful pregnancy. Moreover, in cases of silent heats or prolonged estrus, where behavioral cues may not align with the actual ovulation event, progesterone measurements offer an unerring guide to fertility.

Beyond its role in optimizing breeding outcomes, progesterone assays serve as diagnostic lighthouses in the sea of reproductive health. Ovarian disorders, encompassing conditions like ovarian cysts or luteinization failure, can disrupt the delicate hormonal balance necessary for reproductive success. Progesterone measurements unveil these irregularities, offering valuable insights into the underlying causes of infertility or breeding difficulties. Armed with this knowledge, veterinarians can formulate targeted treatment strategies, addressing the root causes of reproductive challenges.

The significance of progesterone testing extends to the realm of clinical diagnostics. It emerges as an invaluable tool for the early diagnosis of pseudopregnancy, a condition where a non-pregnant female exhibits symptoms akin to pregnancy. Progesterone measurements help differentiate true pregnancy from pseudopregnancy, sparing the dog unnecessary interventions while providing peace of mind to caregivers.

Furthermore, progesterone assays are instrumental in identifying pyometra, a potentially life-threatening uterine infection. Elevated progesterone levels in combination with clinical symptoms can sound the alarm, prompting immediate medical intervention. Early diagnosis is paramount in pyometra cases, as timely treatment significantly improves the likelihood of a positive outcome.

In the realm of scientific exploration, progesterone measurements open windows to understanding the complexities of canine reproduction. Researchers leverage this data to unravel the intricacies of the hormonal symphony orchestrating fertility and pregnancy in dogs. The dynamic changes in progesterone levels throughout the reproductive cycle provide a treasure trove of information, aiding in the advancement of veterinary science and reproductive biology.

In summation, the measurement of progesterone levels in female dogs is not merely a technical procedure; it is a compass guiding breeders, a diagnostic tool fortifying clinical practice, and a beacon illuminating the path of scientific discovery. It stands as an embodiment of comprehensive reproductive care, ensuring the well-being of both canine mothers and their progeny while advancing our knowledge of this fundamental aspect of canine biology.

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