Canine RLN antibody and antigen (recombinant protein)

Diagnostic anti-Canine RLN antibodies pairs and antigen for animal health (animal Dog/Canine Hormone disorders) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-CAN-RLN-Ag01 Relaxin (RLN) $3090.00
GMP-CAN-RLN-Ab01 Anti-Canine RLN mouse monoclonal antibody (mAb) $3090.00
GMP-CAN-RLN-Ab02 Anti-Canine RLN mouse monoclonal antibody (mAb) $3090.00
GMP-CAN-RLN-Ab03 Anti-Canine RLN human monoclonal antibody (mAb) $3090.00
GMP-CAN-RLN-Ab04 Anti-Canine RLN human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-RLN-Ag01
Product Name Relaxin (RLN)
Target/Biomarker Relaxin (RLN)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Canine RLN antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Relaxin (RLN) level test of animal Dog/Canine with Hormone disorders.
Tag His
Reconized/Reactive Specics Relaxin (RLN)
Product description Recombinant Canine RLN protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-CAN-RLN-Ab01,GMP-CAN-RLN-Ab02
Target/Biomarker Relaxin (RLN)
Product Name Anti-Canine RLN mouse monoclonal antibody (mAb)
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Recombinant Canine RLN antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Relaxin (RLN) antibodies in Relaxin (RLN) level test of animal Dog/Canine with Hormone disorders.
Product description Anti-Canine RLN mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Relaxin (RLN) antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-CAN-RLN-Ab03,GMP-CAN-RLN-Ab04
Target/Biomarker Relaxin (RLN)
Product Name Anti-Canine RLN human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Canine RLN antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Relaxin (RLN) antibodies in Relaxin (RLN) level test of animal Dog/Canine with Hormone disorders.
Product description Anti-Canine RLN mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker Information


    The measurement of relaxin levels in female dogs emerges as a multifaceted tool, wielding profound implications in clinical practice, scientific exploration, and the broader landscape of canine well-being.

    In the realm of clinical diagnostics, relaxin testing serves as a powerful sentinel of pregnancy. Its unique and reliable elevation during gestation positions it as a gold standard for confirming pregnancy in female dogs. Veterinarians and breeders rely on relaxin assays to provide conclusive evidence of pregnancy, instilling confidence and assurance in both canine caregivers and practitioners alike. This non-invasive, accurate method supersedes traditional methods and offers a sensitive and specific means of detecting early-stage pregnancies.

    Moreover, relaxin measurements offer a critical differentiation between true pregnancy and pseudopregnancy, a condition where non-pregnant females exhibit symptoms resembling those of gestation. This diagnostic clarity ensures that dogs receive the appropriate care and intervention, minimizing unnecessary stress and interventions.

    The scientific import of relaxin extends far beyond the clinic. Researchers leverage relaxin data to illuminate the intricate web of molecular signals and pathways that govern pregnancy and tissue remodeling in dogs. The dynamic changes in relaxin levels throughout gestation offer a window into the complex and elegant coordination of physiological processes. These insights have broad implications, contributing not only to advancements in veterinary science but also enhancing our understanding of the broader field of reproductive biology.

    Additionally, relaxin testing plays a pivotal role in the ongoing monitoring of pregnancy in dogs. By assessing relaxin levels at various stages, veterinarians and researchers gain valuable insights into the health and well-being of both the expectant mother and her developing litter. This information guides clinical decisions, ensuring the provision of optimal care and support throughout the entirety of gestation.

    In the broader context of canine welfare, the measurement of relaxin levels embodies a commitment to the health and happiness of our canine companions. It is an emblem of our dedication to ensuring the well-being of expectant mothers and their offspring, guaranteeing safe and successful pregnancies, and providing caregivers with the peace of mind that comes with accurate diagnostics.

    In summation, the measurement of relaxin levels in female dogs serves as a cornerstone of clinical excellence, a portal to scientific discovery, and a testament to our devotion to the health and happiness of our canine companions. It is a testament to the power of scientific inquiry, offering a deeper understanding of the intricate processes governing pregnancy and tissue remodeling while safeguarding the well-being of expectant mothers and their progeny., Relaxin, a multifaceted peptide hormone, takes center stage in the intricate drama of reproductive physiology and tissue remodeling in mammals, including humans and dogs. This remarkable hormone, a member of the insulin/relaxin superfamily, stands as a testament to the intricate interplay of molecular signals governing pivotal life processes.

    Structurally, relaxin is characterized by its complex chain of amino acids, and its synthesis primarily occurs in the corpus luteum during pregnancy. This temporary endocrine gland within the ovaries emerges post-ovulation and serves as the primary source of relaxin production.

    In the context of pregnancy, relaxin orchestrates a symphony of physiological changes to ensure the successful progression of gestation. Among its primary roles is the promotion of uterine relaxation. By relaxing the smooth muscles of the uterus, relaxin prevents premature contractions, providing a safe environment for the developing fetus. This uterine relaxation also facilitates the dilation of the cervix during labor, allowing for the passage of the newborn.

    Beyond its impact on uterine and cervical physiology, relaxin extends its reach to the cardiovascular system. During pregnancy, it plays a crucial role in vasodilation, leading to the expansion of blood vessels. This adaptive response ensures increased blood flow to the uterus and placenta, facilitating the exchange of vital nutrients and oxygen between the mother and the developing embryo. It is this finely orchestrated vascular dance that supports the nourishment and growth of the fetus.

    Interestingly, relaxin's influence isn't confined to pregnancy alone. It also plays a role in tissue remodeling, affecting processes such as wound healing and collagen metabolism. In these contexts, relaxin promotes the breakdown of collagen, the principal structural protein in connective tissues. This effect can be particularly relevant in the management of conditions involving fibrosis or scar tissue formation.



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