Canine TG antibody and antigen (recombinant protein)

Diagnostic anti-Canine TG antibodies pairs and antigen for animal health (animal Dog/Canine thyroid nodules, thyroid adenomas, multinodular goiters, thyrotoxicosis, thyroid cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-TG-Ag01Canine TG$3090.00
GMP-CAN-TG-Ab01Anti-Canine TG mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-TG-Ab02Anti-Canine TG mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-TG-Ab03Anti-Canine TG human monoclonal antibody (mAb)$3090.00
GMP-CAN-TG-Ab04Anti-Canine TG human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-TG-Ag01
Product NameCanine TG
Target/BiomarkerCanine TG
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine TG antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TG level test of animal Dog/Canine with thyroid nodules, thyroid adenomas, multinodular goiters, thyrotoxicosis, thyroid cancer.
TagHis
Reconized/Reactive SpecicsCanine TG
Product descriptionRecombinant Canine TG protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-TG-Ab01,GMP-CAN-TG-Ab02
Target/BiomarkerCanine TG
Product NameAnti-Canine TG mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine TG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TG antibodies in Canine TG level test of animal Dog/Canine with thyroid nodules, thyroid adenomas, multinodular goiters, thyrotoxicosis, thyroid cancer.
Product descriptionAnti-Canine TG mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TG antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-TG-Ab03,GMP-CAN-TG-Ab04
Target/BiomarkerCanine TG
Product NameAnti-Canine TG human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine TG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TG antibodies in Canine TG level test of animal Dog/Canine with thyroid nodules, thyroid adenomas, multinodular goiters, thyrotoxicosis, thyroid cancer.
Product descriptionAnti-Canine TG mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    In dogs (canines), "TG" typically refers to triglycerides, which are a type of fat (lipid) found in the blood. Triglycerides are derived from the fats eaten in foods or are made in the body from other energy sources, such as carbohydrates. When a dog eats, any calories it doesn't need to use immediately are converted into triglycerides and stored in fat cells. Hormones later release triglycerides for energy between meals.

    Importance of Triglycerides in Dogs

    Triglycerides serve as a major source of energy for the body, but high levels of triglycerides in the blood (hypertriglyceridemia) can be a marker for various health issues in dogs, including:

    Pancreatitis: This is an inflammation of the pancreas that can be acute or chronic. High triglyceride levels are a risk factor for the development of pancreatitis in dogs.

    Obesity: Elevated triglyceride levels are often seen in obese dogs, which can predispose them to other health conditions such as diabetes mellitus, cardiovascular disease, and joint problems.

    Diabetes Mellitus: Dogs with diabetes may have high triglyceride levels due to the altered metabolism associated with insulin deficiency or resistance.

    Hypothyroidism: This condition, caused by an underactive thyroid gland, can lead to elevated triglyceride levels as part of a broader spectrum of metabolic disturbances.

    Cushing’s Disease (Hyperadrenocorticism): This endocrine disorder can cause a variety of symptoms, including increased triglyceride levels.

    Diagnosis and Monitoring

    Blood Tests: The diagnosis of high triglyceride levels is made through blood tests, which measure the lipid profile of the dog. It's important for dogs to fast for 8-12 hours before a lipid profile test to get accurate measurements of triglyceride levels.

    Monitoring: Dogs with known risk factors for high triglycerides, such as those with obesity, diabetes, or pancreatitis, should have their levels monitored regularly as part of their health management plan.

    Treatment and Management

    Dietary Management: Often, the first step in managing high triglyceride levels is through dietary changes. Diets low in fat and high in fiber can help manage triglyceride levels.

    Weight Management: For obese dogs, weight loss can help lower triglyceride levels and reduce the risk of associated diseases.

    Medication: In some cases, medication may be necessary to manage underlying conditions contributing to high triglyceride levels, such as hypothyroidism or diabetes.

    Regular Exercise: Regular physical activity can help manage weight and lower triglycerides.

    Prevention

    Preventive measures include maintaining a healthy diet and weight, regular exercise, and routine veterinary check-ups to identify and manage any underlying health issues before they lead to elevated triglyceride levels.

    In summary, while triglycerides play a crucial role in providing energy for dogs, monitoring and managing their levels is important for preventing and managing various health conditions. Regular veterinary care is essential to maintaining the health and well-being of dogs, particularly those at risk for high triglyceride levels.



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