Canine cIV antibody and antigen (recombinant protein)

Diagnostic anti-Canine cIV antibodies pairs and antigen for animal health (animal Dog/Canine Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury.) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-cIV-Ag01Canine cIV$3090.00
GMP-CAN-cIV-Ab01Anti-Canine cIV mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-cIV-Ab02Anti-Canine cIV mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-cIV-Ab03Anti-Canine cIV human monoclonal antibody (mAb)$3090.00
GMP-CAN-cIV-Ab04Anti-Canine cIV human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-cIV-Ag01
Product NameCanine cIV
Target/BiomarkerCanine cIV
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine cIV antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of animal Dog/Canine with Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
TagHis
Reconized/Reactive SpecicsCanine cIV
Product descriptionRecombinant Canine cIV protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-cIV-Ab01,GMP-CAN-cIV-Ab02
Target/BiomarkerCanine cIV
Product NameAnti-Canine cIV mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine cIV antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine cIV antibodies in Canine cIV level test of animal Dog/Canine with Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Product descriptionAnti-Canine cIV mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine cIV antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-cIV-Ab03,GMP-CAN-cIV-Ab04
Target/BiomarkerCanine cIV
Product NameAnti-Canine cIV human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine cIV antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine cIV antibodies in Canine cIV level test of animal Dog/Canine with Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Product descriptionAnti-Canine cIV mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Collagen Type IV (cIV) stands as an unassuming yet indispensable structural component in the intricate web of canine physiology. As a member of the collagen family, it shoulders the monumental responsibility of maintaining the integrity of basement membranes, a role that resonates throughout the canine body.

    Structurally, cIV is a collagen protein comprising three polypeptide chains intertwined in a triple helical structure. This unique arrangement lends both strength and flexibility to cIV, making it an ideal candidate for the rigorous task of supporting basement membranes. These membranes are the unsung heroes beneath the scenes, forming a delicate yet robust interface between cells and the surrounding extracellular matrix.

    Basement membranes are not merely passive barriers; they are dynamic regulators of cellular activities. cIV plays a multifaceted role within these membranes. It provides the structural framework, ensuring that basement membranes maintain their structural integrity even under mechanical stresses. Additionally, cIV interacts with various proteins and signaling molecules, contributing to the filtration properties of basement membranes and orchestrating essential cellular signaling events.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.