Canine fFN antibody and antigen (recombinant protein)

Diagnostic anti-Canine fFN antibodies pairs and antigen for animal health (animal Dog/Canine premature delivery) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-fFN-Ag01Canine fFN$3090.00
GMP-CAN-fFN-Ab01Anti-Canine fFN mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-fFN-Ab02Anti-Canine fFN mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-fFN-Ab03Anti-Canine fFN human monoclonal antibody (mAb)$3090.00
GMP-CAN-fFN-Ab04Anti-Canine fFN human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-fFN-Ag01
Product NameCanine fFN
Target/BiomarkerCanine fFN
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine fFN antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in fFN level test of animal Dog/Canine with premature delivery.
TagHis
Reconized/Reactive SpecicsCanine fFN
Product descriptionRecombinant Canine fFN protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-fFN-Ab01,GMP-CAN-fFN-Ab02
Target/BiomarkerCanine fFN
Product NameAnti-Canine fFN mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine fFN antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine fFN antibodies in Canine fFN level test of animal Dog/Canine with premature delivery.
Product descriptionAnti-Canine fFN mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine fFN antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-fFN-Ab03,GMP-CAN-fFN-Ab04
Target/BiomarkerCanine fFN
Product NameAnti-Canine fFN human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine fFN antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine fFN antibodies in Canine fFN level test of animal Dog/Canine with premature delivery.
Product descriptionAnti-Canine fFN mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Fetal Fibronectin (c-fFN) is a remarkable biomarker intricately woven into the tapestry of canine reproductive biology. This glycoprotein, uniquely found within the amniotic fluid and placental tissues of pregnant dogs, holds the pivotal responsibility of securing the bonds that sustain pregnancy. Structurally, c-fFN is part of the fibronectin family, a group of adhesive proteins that play crucial roles in cell adhesion and tissue organization.

    The primary mission of c-fFN is to serve as a molecular adhesive. During pregnancy, it acts as the glue that binds the developing canine embryos to the uterine wall. This adhesion is not merely a structural function; it is the foundation upon which the entire pregnancy relies. Without the stable connection c-fFN provides, the developing pups would be at risk of detachment from the uterine lining, leading to a host of potential complications.

    Beyond its adhesive properties, c-fFN plays a strategic role in immune regulation. Pregnancy represents a unique challenge for the maternal immune system, as it must tolerate the presence of semi-allogeneic embryos—offspring that share some, but not all, genetic material with the mother. c-fFN contributes to immune tolerance, ensuring that the mother's immune system does not mount a hostile response against the developing embryos. This immunomodulatory function is crucial for the success of canine pregnancies.



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    GDU

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