Canine proBNP antibody and antigen (recombinant protein)

Diagnostic anti-Canine proBNP antibodies pairs and antigen for animal health (animal Dog/Canine intrinsic cardiac dysfunction) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-proBNP-Ag01Canine proBNP$3090.00
GMP-CAN-proBNP-Ab01Anti-Canine proBNP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-proBNP-Ab02Anti-Canine proBNP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-proBNP-Ab03Anti-Canine proBNP human monoclonal antibody (mAb)$3090.00
GMP-CAN-proBNP-Ab04Anti-Canine proBNP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-proBNP-Ag01
Product NameCanine proBNP
Target/BiomarkerCanine proBNP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine proBNP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in proBNP level test of animal Dog/Canine with intrinsic cardiac dysfunction.
TagHis
Reconized/Reactive SpecicsCanine proBNP
Product descriptionRecombinant Canine proBNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-proBNP-Ab01,GMP-CAN-proBNP-Ab02
Target/BiomarkerCanine proBNP
Product NameAnti-Canine proBNP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine proBNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine proBNP antibodies in Canine proBNP level test of animal Dog/Canine with intrinsic cardiac dysfunction.
Product descriptionAnti-Canine proBNP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine proBNP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-proBNP-Ab03,GMP-CAN-proBNP-Ab04
Target/BiomarkerCanine proBNP
Product NameAnti-Canine proBNP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine proBNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine proBNP antibodies in Canine proBNP level test of animal Dog/Canine with intrinsic cardiac dysfunction.
Product descriptionAnti-Canine proBNP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine proBNP, or Pro B-type natriuretic peptide, represents a remarkable advancement in our ability to understand and assess cardiac health in dogs. To grasp its significance fully, one must delve into its molecular intricacies and its role as a diagnostic beacon in the world of veterinary cardiology.

    At its core, proBNP is a prohormone synthesized predominantly within the cardiomyocytes, or heart muscle cells, of dogs. It belongs to the natriuretic peptide family, which includes B-type natriuretic peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP). When the heart encounters increased stress or stretching, a common occurrence in various cardiac conditions, proBNP undergoes enzymatic cleavage to release both BNP and NT-proBNP.

    BNP, the active hormone, exerts its effects by acting as a vasodilator. It plays a vital role in regulating blood pressure and fluid balance in the body. By relaxing blood vessels, BNP helps reduce blood pressure and alleviate the workload on the heart. However, its elevation in circulation signifies that the heart is struggling to maintain its normal function. This is where proBNP becomes a crucial indicator of cardiac distress.

    NT-proBNP, on the other hand, remains stable in circulation for an extended period, allowing for a broader diagnostic window. Together, BNP and NT-proBNP provide veterinarians with a comprehensive view of cardiac health and the extent of cardiac stress.



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