Canine sFlt-1 antibody and antigen (recombinant protein)
Diagnostic anti-Canine sFlt-1 antibodies pairs and antigen for animal health (animal Dog/Canine ascular diseases and cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-CAN-sFlt-1-Ag01 | Canine sFlt-1 | $3090.00 |
GMP-CAN-sFlt-1-Ab01 | Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) | $3090.00 |
GMP-CAN-sFlt-1-Ab02 | Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) | $3090.00 |
GMP-CAN-sFlt-1-Ab03 | Anti-Canine sFlt-1 human monoclonal antibody (mAb) | $3090.00 |
GMP-CAN-sFlt-1-Ab04 | Anti-Canine sFlt-1 human monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-CAN-sFlt-1-Ag01 |
Product Name | Canine sFlt-1 |
Target/Biomarker | Canine sFlt-1 |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Canine sFlt-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer. |
Tag | His | Reconized/Reactive Specics | Canine sFlt-1 |
Product description | Recombinant Canine sFlt-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-CAN-sFlt-1-Ab01,GMP-CAN-sFlt-1-Ab02 |
Target/Biomarker | Canine sFlt-1 |
Product Name | Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Canine sFlt-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sFlt-1 antibodies in Canine sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer. |
Product description | Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sFlt-1 antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-CAN-sFlt-1-Ab03,GMP-CAN-sFlt-1-Ab04 |
Target/Biomarker | Canine sFlt-1 |
Product Name | Anti-Canine sFlt-1 human monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Recombinant Canine sFlt-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sFlt-1 antibodies in Canine sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer. |
Product description | Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Soluble Fms-Like Tyrosine Kinase-1 (sFlt-1) in dogs (canines) is a pivotal biomarker with multifaceted roles in vascular health and angiogenesis regulation. It is a soluble receptor that functions by binding to and neutralizing vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), thereby modulating their biological effects. In healthy adult dogs, sFlt-1 levels are typically tightly regulated, contributing to the maintenance of normal vascular function.
Structurally, sFlt-1 is a truncated form of the transmembrane receptor, Fms-like tyrosine kinase-1 (Flt-1). Unlike the membrane-bound form, sFlt-1 lacks the transmembrane domain, making it soluble and capable of circulating in the bloodstream. This solubility allows sFlt-1 to act as a decoy receptor, sequestering VEGF and PlGF and preventing them from binding to their cellular receptors.
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