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Canine sST2 antibody and antigen (recombinant protein)
Diagnostic anti-Canine sST2 antibodies pairs and antigen for animal health (animal Dog/Canine chronic and acute heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-sST2-Ag01 | Canine sST2 | $3090.00 |
| GMP-CAN-sST2-Ab01 | Anti-Canine sST2 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-sST2-Ab02 | Anti-Canine sST2 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-sST2-Ab03 | Anti-Canine sST2 human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-sST2-Ab04 | Anti-Canine sST2 human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-sST2-Ag01 |
| Product Name | Canine sST2 |
| Target/Biomarker | Canine sST2 |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine sST2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sST2 level test of animal Dog/Canine with chronic and acute heart failure. |
| Tag | His | Reconized/Reactive Specics | Canine sST2 |
| Product description | Recombinant Canine sST2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-sST2-Ab01,GMP-CAN-sST2-Ab02 |
| Target/Biomarker | Canine sST2 |
| Product Name | Anti-Canine sST2 mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sST2 antibodies in Canine sST2 level test of animal Dog/Canine with chronic and acute heart failure. |
| Product description | Anti-Canine sST2 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sST2 antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-sST2-Ab03,GMP-CAN-sST2-Ab04 |
| Target/Biomarker | Canine sST2 |
| Product Name | Anti-Canine sST2 human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine sST2 antibodies in Canine sST2 level test of animal Dog/Canine with chronic and acute heart failure. |
| Product description | Anti-Canine sST2 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Soluble ST2 (sST2) in dogs is a soluble receptor that plays a pivotal role in the intricate web of immune responses, inflammation regulation, and cardiac health. It represents a key component in the cascade of events that unfold during cardiac stress, injury, or inflammation.
In greater detail, sST2 is a product of the ST2 gene and exists in two primary forms: the membrane-bound ST2L and the soluble sST2. ST2L serves as a receptor for interleukin-33 (IL-33), an interleukin associated with anti-inflammatory and protective effects in the cardiovascular system. When IL-33 binds to membrane-bound ST2L, it contributes to cardiac protection and immune regulation.
However, sST2, the soluble form of the ST2 receptor, acts as a decoy receptor, neutralizing the beneficial effects of IL-33. In dogs, sST2 is primarily secreted by cardiac cells, particularly cardiomyocytes, in response to cardiac stressors, inflammation, or injury. Its presence in the bloodstream indicates an activated immune response and an underlying cardiac issue.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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