Equine ACTH antibody and antigen (recombinant protein)

Diagnostic anti-Equine ACTH antibodies pairs and antigen for animal health (animal Equine/Horse pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-ACTH-Ag01Equine ACTH$3090.00
GMP-EQU-ACTH-Ab01Anti-Equine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-ACTH-Ab02Anti-Equine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-ACTH-Ab03Anti-Equine ACTH human monoclonal antibody (mAb)$3090.00
GMP-EQU-ACTH-Ab04Anti-Equine ACTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-ACTH-Ag01
Product NameEquine ACTH
Target/BiomarkerEquine ACTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine ACTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACTH level test of animal Equine/Horse with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
TagHis
Reconized/Reactive SpecicsEquine ACTH
Product descriptionRecombinant Equine ACTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-ACTH-Ab01,GMP-EQU-ACTH-Ab02
Target/BiomarkerEquine ACTH
Product NameAnti-Equine ACTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ACTH antibodies in Equine ACTH level test of animal Equine/Horse with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Equine ACTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ACTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-ACTH-Ab03,GMP-EQU-ACTH-Ab04
Target/BiomarkerEquine ACTH
Product NameAnti-Equine ACTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ACTH antibodies in Equine ACTH level test of animal Equine/Horse with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Equine ACTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Adrenocorticotropic Hormone (ACTH) takes center stage in the intricate web of equine endocrinology, serving as the linchpin that orchestrates the horse's response to stressors and maintains hormonal balance. Structurally, ACTH is a 39-amino acid peptide hormone synthesized and secreted by the anterior pituitary gland. It belongs to the melanocortin family, a group of hormones with multifaceted physiological roles.

    ACTH's primary mission lies in its regulation of the adrenal glands, specifically the adrenal cortex. When a horse encounters stressors or experiences shifts in its internal environment, the hypothalamus promptly releases corticotropin-releasing hormone (CRH). CRH, in turn, stimulates the anterior pituitary gland to release ACTH into the bloodstream.

    In its journey through circulation, ACTH reaches the adrenal cortex, where it binds to specific receptors on the surface of adrenal cells. This binding event triggers intracellular processes that culminate in the synthesis and release of cortisol, a corticosteroid hormone. Often referred to as the "stress hormone," cortisol exerts a wide array of effects on equine physiology.

    Cortisol holds the reins in regulating metabolism, influencing immune function, and steering the horse's response to stressors. It elevates blood glucose levels, modulates immune responses, and orchestrates anti-inflammatory actions. Furthermore, cortisol influences protein and fat metabolism, maintains electrolyte balance, and exerts its influence on cardiovascular function.



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