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Equine AI antibody and antigen (recombinant protein)
Diagnostic anti-Equine AI antibodies pairs and antigen for animal health (animal Equine/Horse hypertension, renal disease, and congestive heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-EQU-AI-Ag01 | Equine AI | $3090.00 |
| GMP-EQU-AI-Ab01 | Anti-Equine AI mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-EQU-AI-Ab02 | Anti-Equine AI mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-EQU-AI-Ab03 | Anti-Equine AI human monoclonal antibody (mAb) | $3090.00 |
| GMP-EQU-AI-Ab04 | Anti-Equine AI human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-EQU-AI-Ag01 |
| Product Name | Equine AI |
| Target/Biomarker | Equine AI |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Equine AI antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AI level test of animal Equine/Horse with hypertension, renal disease, and congestive heart failure. |
| Tag | His | Reconized/Reactive Specics | Equine AI |
| Product description | Recombinant Equine AI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-EQU-AI-Ab01,GMP-EQU-AI-Ab02 |
| Target/Biomarker | Equine AI |
| Product Name | Anti-Equine AI mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Equine AI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine AI antibodies in Equine AI level test of animal Equine/Horse with hypertension, renal disease, and congestive heart failure. |
| Product description | Anti-Equine AI mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine AI antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-EQU-AI-Ab03,GMP-EQU-AI-Ab04 |
| Target/Biomarker | Equine AI |
| Product Name | Anti-Equine AI human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Equine AI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine AI antibodies in Equine AI level test of animal Equine/Horse with hypertension, renal disease, and congestive heart failure. |
| Product description | Anti-Equine AI mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Equine Alpha-2 Macroglobulin (EAMG) is an intriguing biomarker that holds profound significance in understanding the health and physiology of horses. Its structural and functional complexity makes it a key player in the equine biological landscape.
At a molecular level, EAMG is a high-molecular-weight glycoprotein composed of four identical subunits arranged in a tetrameric structure. This unique architecture grants EAMG its remarkable versatility and functionality. Its primary role lies in the inhibition of proteases, enzymes that play pivotal roles in various physiological processes. EAMG acts as a sentinel, intercepting proteases involved in inflammatory responses, tissue remodeling, and pathogen defense. By inactivating these proteases, EAMG helps maintain tissue integrity and prevent excessive inflammation, thereby safeguarding the horse's health.
Beyond its role as a protease inhibitor, EAMG has a multifaceted immunomodulatory function. During an immune challenge or infection, the horse's body mounts an acute-phase response. EAMG is an integral part of this response, with its concentration in the blood rising significantly. This increase aids in the clearance of pathogens, such as bacteria and viruses, by neutralizing their protease weaponry. Moreover, EAMG helps orchestrate the inflammatory response, ensuring it is targeted and controlled to prevent collateral damage to healthy tissues.
Equally fascinating is EAMG's involvement in the transportation of vital molecules within the horse's circulatory system. This biomarker acts as a molecular courier, shuttling hormones, vitamins, growth factors, and other essential compounds to their respective destinations within the horse's body. This function is fundamental to the regulation of numerous metabolic processes, including growth, tissue repair, and overall homeostasis.
In summary, Equine Alpha-2 Macroglobulin (EAMG) is a molecular marvel within the equine system. Its structural complexity and multifunctional nature make it an essential player in maintaining the health and well-being of horses.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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