Equine ApoE antibody and antigen (recombinant protein)

Diagnostic anti-Equine ApoE antibodies pairs and antigen for animal health (animal Equine/Horse Cardiovascular Disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-ApoE-Ag01Equine ApoE$3090.00
GMP-EQU-ApoE-Ab01Anti-Equine ApoE mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-ApoE-Ab02Anti-Equine ApoE mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-ApoE-Ab03Anti-Equine ApoE human monoclonal antibody (mAb)$3090.00
GMP-EQU-ApoE-Ab04Anti-Equine ApoE human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-ApoE-Ag01
Product NameEquine ApoE
Target/BiomarkerEquine ApoE
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine ApoE antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ApoE level test of animal Equine/Horse with Cardiovascular Disease.
TagHis
Reconized/Reactive SpecicsEquine ApoE
Product descriptionRecombinant Equine ApoE protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-ApoE-Ab01,GMP-EQU-ApoE-Ab02
Target/BiomarkerEquine ApoE
Product NameAnti-Equine ApoE mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine ApoE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ApoE antibodies in Equine ApoE level test of animal Equine/Horse with Cardiovascular Disease.
Product descriptionAnti-Equine ApoE mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ApoE antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-ApoE-Ab03,GMP-EQU-ApoE-Ab04
Target/BiomarkerEquine ApoE
Product NameAnti-Equine ApoE human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine ApoE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine ApoE antibodies in Equine ApoE level test of animal Equine/Horse with Cardiovascular Disease.
Product descriptionAnti-Equine ApoE mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Apolipoprotein E, often referred to as Equine ApoE, is a multifaceted protein that occupies a central role in the intricate domain of equine physiology. Predominantly synthesized in the liver of domestic horses (Equus ferus caballus), this glycoprotein exhibits a unique structural feature marked by carbohydrates attached to its polypeptide chain. As a distinguished member of the apolipoprotein family, Equine ApoE orchestrates a complex symphony of lipid metabolism, with a particular emphasis on cholesterol management within the equine body.

    The prominence of Equine ApoE comes to the forefront in its association with high-density lipoproteins (HDL), commonly hailed as "good cholesterol." HDL particles, acting as custodians of cholesterol and lipids in the equine bloodstream, rely significantly on Equine ApoE for their structural integrity and functional prowess. This biomarker serves as an integral component of HDLs, contributing not only to their structural integrity but also to their dynamic role in the reverse cholesterol transport pathway.

    The choreography of cholesterol transport begins with Equine ApoE. It binds to lipids, effectively transforming nascent HDL particles into active carriers of excess cholesterol. These HDLs embark on a journey to peripheral tissues, where they retrieve surplus cholesterol and lipids, subsequently venturing back to the liver. In the liver, cholesterol undergoes metabolism and eventual excretion, ensuring the maintenance of optimal cholesterol levels within the equine body.



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