Equine CBL antibody and antigen (recombinant protein)

Diagnostic anti-Equine CBL antibodies pairs and antigen for animal health (animal Equine/Horse ectopia lentis, learning difficulties and skeletal abnormalities) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-CBL-Ag01Equine CBL$3090.00
GMP-EQU-CBL-Ab01Anti-Equine CBL mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-CBL-Ab02Anti-Equine CBL mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-CBL-Ab03Anti-Equine CBL human monoclonal antibody (mAb)$3090.00
GMP-EQU-CBL-Ab04Anti-Equine CBL human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-CBL-Ag01
Product NameEquine CBL
Target/BiomarkerEquine CBL
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine CBL antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CBL level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
TagHis
Reconized/Reactive SpecicsEquine CBL
Product descriptionRecombinant Equine CBL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-CBL-Ab01,GMP-EQU-CBL-Ab02
Target/BiomarkerEquine CBL
Product NameAnti-Equine CBL mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine CBL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine CBL antibodies in Equine CBL level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Product descriptionAnti-Equine CBL mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine CBL antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-CBL-Ab03,GMP-EQU-CBL-Ab04
Target/BiomarkerEquine CBL
Product NameAnti-Equine CBL human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine CBL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine CBL antibodies in Equine CBL level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Product descriptionAnti-Equine CBL mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cobalamin, or Vitamin B12, is an intriguing biochemical cornerstone within the equine (horse) community. This water-soluble vitamin, represented by the biomarker CBL, plays a pivotal role in a plethora of metabolic pathways that are vital for equine health and vigor.

    Structurally, Vitamin B12 boasts a complex molecular arrangement with a central cobalt atom. This cobalt atom is the linchpin of Vitamin B12's biological activity, crucial for its role as a coenzyme in enzymatic reactions that are foundational to equine physiology.

    One of Vitamin B12's critical functions is its involvement in the metabolic conversion of methylmalonyl-CoA to succinyl-CoA, a process catalyzed by methylmalonyl-CoA mutase. This conversion is of immense significance, as it contributes to the metabolism of amino acids and fatty acids, which are essential for the energy production and overall cellular function in horses. Furthermore, Vitamin B12 actively participates in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methionine is a fundamental amino acid and serves as the precursor for protein synthesis, making it indispensable for equine growth and muscle development.

    Beyond these vital functions, Vitamin B12 is crucial for DNA synthesis in horses. It supports the production of thymidine, one of the four nucleotide building blocks of DNA. This role is pivotal for equine growth, tissue repair, and overall development.

    Vitamin B12's significance further extends to the synthesis of myelin, the insulating sheath that envelops nerve fibers. In doing so, it ensures the efficient transmission of nerve impulses, underpinning neurological function. Additionally, Vitamin B12 plays a key role in heme synthesis, a vital component of hemoglobin within red blood cells. Hemoglobin's function in oxygen transport makes it central to equine vitality and performance.



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    GDU

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