Equine FER antibody and antigen (recombinant protein)

Diagnostic anti-Equine FER antibodies pairs and antigen for animal health (animal Equine/Horse hemochromatosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-FER-Ag01Equine FER$3090.00
GMP-EQU-FER-Ab01Anti-Equine FER mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-FER-Ab02Anti-Equine FER mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-FER-Ab03Anti-Equine FER human monoclonal antibody (mAb)$3090.00
GMP-EQU-FER-Ab04Anti-Equine FER human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-FER-Ag01
Product NameEquine FER
Target/BiomarkerEquine FER
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine FER antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FER level test of animal Equine/Horse with hemochromatosis.
TagHis
Reconized/Reactive SpecicsEquine FER
Product descriptionRecombinant Equine FER protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-FER-Ab01,GMP-EQU-FER-Ab02
Target/BiomarkerEquine FER
Product NameAnti-Equine FER mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine FER antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FER antibodies in Equine FER level test of animal Equine/Horse with hemochromatosis.
Product descriptionAnti-Equine FER mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FER antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-FER-Ab03,GMP-EQU-FER-Ab04
Target/BiomarkerEquine FER
Product NameAnti-Equine FER human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine FER antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FER antibodies in Equine FER level test of animal Equine/Horse with hemochromatosis.
Product descriptionAnti-Equine FER mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    FER, the Fer protein, is a multifaceted biomarker that holds a central position in the cellular landscape of horses (equines). This non-receptor tyrosine kinase is widely expressed across various equine tissues and cell types, underpinning its importance in both normal physiological processes and pathological conditions.

    Structurally, FER comprises distinct domains, including an N-terminal FER tyrosine kinase domain and a C-terminal domain specialized in protein-protein interactions. This molecular architecture equips FER with the ability to phosphorylate target proteins, thereby modulating intricate intracellular signaling pathways. FER's multifunctional nature positions it as a conductor of cellular functions in equines.

    A pivotal role of FER in horses is its participation in the regulation of cell growth and proliferation. This non-receptor tyrosine kinase serves as a critical checkpoint in the complex signaling networks that govern cellular division. When FER activity is perturbed or dysregulated, it can trigger uncontrolled cell growth, a cardinal feature of cancer. This aspect of FER biology holds profound implications for veterinary oncology. By measuring FER levels and scrutinizing its activity within equine tumors, clinicians can gain invaluable insights into cancer behavior, anticipate patient responses to treatments, and tailor therapeutic interventions for more favorable outcomes. Furthermore, ongoing investigations into FER's role in specific equine cancer types may uncover novel therapeutic targets, bolstering the field of equine oncology.



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    GDU

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