Equine FIB antibody and antigen (recombinant protein)

Diagnostic anti-Equine FIB antibodies pairs and antigen for animal health (animal Equine/Horse congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-FIB-Ag01Equine FIB$3090.00
GMP-EQU-FIB-Ab01Anti-Equine FIB mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-FIB-Ab02Anti-Equine FIB mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-FIB-Ab03Anti-Equine FIB human monoclonal antibody (mAb)$3090.00
GMP-EQU-FIB-Ab04Anti-Equine FIB human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-FIB-Ag01
Product NameEquine FIB
Target/BiomarkerEquine FIB
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine FIB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FIB level test of animal Equine/Horse with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
TagHis
Reconized/Reactive SpecicsEquine FIB
Product descriptionRecombinant Equine FIB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-FIB-Ab01,GMP-EQU-FIB-Ab02
Target/BiomarkerEquine FIB
Product NameAnti-Equine FIB mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FIB antibodies in Equine FIB level test of animal Equine/Horse with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Equine FIB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FIB antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-FIB-Ab03,GMP-EQU-FIB-Ab04
Target/BiomarkerEquine FIB
Product NameAnti-Equine FIB human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine FIB antibodies in Equine FIB level test of animal Equine/Horse with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Equine FIB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Fibrinogen, a linchpin of the equine circulatory system, merits a closer examination. Structurally, it is a glycoprotein of notable complexity, composed of three intertwined polypeptide chains: alpha, beta, and gamma. These chains unite to form a large hexameric molecule with a molecular mass of approximately 340 kDa. Synthesized predominantly in the liver, equine fibrinogen is released into the bloodstream, poised for its critical role in maintaining hemostasis.

    At the heart of Equine Fibrinogen's function lies its conversion to fibrin, an event central to blood clot formation. When vascular injury or other hemostatic triggers occur, the enzyme thrombin catalyzes the cleavage of FIB's alpha and beta chains. This enzymatic reaction liberates fibrin, which undergoes rapid polymerization, creating long strands. These strands intertwine to form a meshwork, the scaffold of a blood clot that effectively halts bleeding.

    The dynamic nature of Equine Fibrinogen renders it a versatile and responsive biomarker. During episodes of inflammation, infection, or tissue injury, its synthesis escalates as part of the acute-phase response. This heightened production equips the body with an enhanced capacity to form blood clots at sites of injury, reinforcing the physiological defense mechanisms against potential threats.



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