Equine HABP antibody and antigen (recombinant protein)

Diagnostic anti-Equine HABP antibodies pairs and antigen for animal health (animal Equine/Horse rheumatoid arthritis (RA) andosteoarthritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-HABP-Ag01Equine HABP$3090.00
GMP-EQU-HABP-Ab01Anti-Equine HABP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-HABP-Ab02Anti-Equine HABP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-HABP-Ab03Anti-Equine HABP human monoclonal antibody (mAb)$3090.00
GMP-EQU-HABP-Ab04Anti-Equine HABP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-HABP-Ag01
Product NameEquine HABP
Target/BiomarkerEquine HABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine HABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HABP level test of animal Equine/Horse with rheumatoid arthritis (RA) andosteoarthritis.
TagHis
Reconized/Reactive SpecicsEquine HABP
Product descriptionRecombinant Equine HABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-HABP-Ab01,GMP-EQU-HABP-Ab02
Target/BiomarkerEquine HABP
Product NameAnti-Equine HABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HABP antibodies in Equine HABP level test of animal Equine/Horse with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Equine HABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-HABP-Ab03,GMP-EQU-HABP-Ab04
Target/BiomarkerEquine HABP
Product NameAnti-Equine HABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HABP antibodies in Equine HABP level test of animal Equine/Horse with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Equine HABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Hyaluronic Acid-Binding Protein (eHABP) emerges as a fundamental player in the intricate world of equine physiology. This glycoprotein, encoded by the eHABP gene, specializes in the orchestration of hyaluronic acid (HA), a prominent constituent of the extracellular matrix. HA's primary role is to maintain tissue hydration, lubrication, and resilience, and eHABP is its faithful guardian in the equine body.

    HA, a high molecular weight polysaccharide, resides in various tissues in horses, including connective tissues, skin, and synovial fluid. Its biophysical properties make it a vital component for proper joint function and overall tissue health. However, HA is prone to degradation and requires constant vigilance to maintain its integrity. This is where eHABP steps in. eHABP forms tight bonds with HA molecules, effectively shielding them from enzymatic degradation and environmental factors.

    The significance of eHABP becomes particularly evident in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating smooth articulation and reducing friction during movement. Without adequate HA levels and efficient HA-binding proteins like eHABP, joints may become susceptible to wear and tear, leading to conditions like osteoarthritis, a painful and debilitating ailment in horses.

    Moreover, eHABP's role extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. In doing so, it supports overall tissue integrity, wound healing, and the body's ability to withstand mechanical stress. Furthermore, eHABP interacts with other proteins and participates in various signaling pathways, influencing processes like tissue repair and inflammation.



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