Equine HE4 antibody and antigen (recombinant protein)

Diagnostic anti-Equine HE4 antibodies pairs and antigen for animal health (animal Equine/Horse ovarian cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-HE4-Ag01Equine HE4$3090.00
GMP-EQU-HE4-Ab01Anti-Equine HE4 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-HE4-Ab02Anti-Equine HE4 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-HE4-Ab03Anti-Equine HE4 human monoclonal antibody (mAb)$3090.00
GMP-EQU-HE4-Ab04Anti-Equine HE4 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-HE4-Ag01
Product NameEquine HE4
Target/BiomarkerEquine HE4
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine HE4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HE4 level test of animal Equine/Horse with ovarian cancer.
TagHis
Reconized/Reactive SpecicsEquine HE4
Product descriptionRecombinant Equine HE4 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-HE4-Ab01,GMP-EQU-HE4-Ab02
Target/BiomarkerEquine HE4
Product NameAnti-Equine HE4 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine HE4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HE4 antibodies in Equine HE4 level test of animal Equine/Horse with ovarian cancer.
Product descriptionAnti-Equine HE4 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HE4 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-HE4-Ab03,GMP-EQU-HE4-Ab04
Target/BiomarkerEquine HE4
Product NameAnti-Equine HE4 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine HE4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine HE4 antibodies in Equine HE4 level test of animal Equine/Horse with ovarian cancer.
Product descriptionAnti-Equine HE4 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    HE4, known scientifically as Human Epididymis Protein 4, is an emerging biomarker with substantial relevance in the field of equine health. Originating from its discovery in humans, HE4 has exhibited homologous counterparts in various species, prominently including horses. It assumes the form of a glycoprotein, primarily manifesting within the equine reproductive system, with specific localization in the epididymis and female reproductive organs.The role of HE4 in equine physiology is multifaceted and of growing interest. One of its critical functions lies in the regulation of ovarian activity. Expression levels of HE4 exhibit dynamic fluctuations during different phases of the estrous cycle, rendering it a pivotal indicator of reproductive status. Notably, this biomarker has also been associated with specific reproductive disorders, thereby serving as an invaluable tool for veterinarians and breeders in monitoring the reproductive health of mares and stallions.

    Beyond its role in reproduction, HE4 holds promise as a marker for various physiological processes in horses. Current research is actively investigating its involvement in immune system modulation and metabolic regulation. These studies suggest that HE4 may be intertwined with the broader health of equine individuals, extending its significance beyond the reproductive realm. As our comprehension of HE4 deepens, it may open doors to innovative diagnostic techniques and therapeutic interventions for diverse equine health conditions, transcending its initial characterization as a reproductive biomarker.

    The scientific exploration of HE4 in the equine context represents an exciting avenue for enhancing our understanding of equine biology, optimizing reproductive management, and potentially revolutionizing the diagnosis and treatment of equine health disorders.|



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