Equine PG I antibody and antigen (recombinant protein)

Diagnostic anti-Equine PG I antibodies pairs and antigen for animal health (animal Equine/Horse atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-PG-I-Ag01Equine PG I$3090.00
GMP-EQU-PG-I-Ab01Anti-Equine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-I-Ab02Anti-Equine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-I-Ab03Anti-Equine PG I human monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-I-Ab04Anti-Equine PG I human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-PG-I-Ag01
Product NameEquine PG I
Target/BiomarkerEquine PG I
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine PG I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
TagHis
Reconized/Reactive SpecicsEquine PG I
Product descriptionRecombinant Equine PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PG-I-Ab01,GMP-EQU-PG-I-Ab02
Target/BiomarkerEquine PG I
Product NameAnti-Equine PG I mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG I antibodies in Equine PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Equine PG I mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG I antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PG-I-Ab03,GMP-EQU-PG-I-Ab04
Target/BiomarkerEquine PG I
Product NameAnti-Equine PG I human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG I antibodies in Equine PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Equine PG I mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine/Horse Pepsinogen I (PG I) emerges as a captivating biomarker, offering a profound glimpse into the intricacies of equine digestion. Structurally, PG I is an inactive zymogen, a precursor to the active enzyme pepsin, and it assumes a central role within the gastric mucosa of the horse's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands.

    The journey of PG I begins with the intake of food. As dietary proteins enter the horse's stomach, PG I stands ready for its metamorphosis into pepsin. This transformation unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG I to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall equine health.

    Beyond its role as a digestive precursor, PG I serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG I is predominantly localized, is crucial for its proper secretion. Disruptions in this mucosal lining, such as those seen in gastric ulcers or gastritis, can alter PG I levels, offering valuable diagnostic insights.



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